antifungal agent

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Related to antimycotic agent: Polyene antibiotics

antifungal agent

see ANTIMICROBIAL AGENT.

antifungal agent 

Any substance which destroys or prevents the growth of fungi. It is one of the antibiotic groups. There are several classes of antifungal drugs: Polyenes, which cause an increase in fungal cell wall permeability leading to its death. Examples: amphotericin B, natamycin, nystatin. Azoles, which act either by inhibiting the synthesis of ergosterol, a component of fungal cell wall or by causing direct wall damage. Examples: clotrimazole, econazole, fluconazole, itraconazole, ketoconazole, miconazole. Pyrimidines, which interfere with the normal function of fungal cells. Example: flucytosine. Syn antimycotic agent.
References in periodicals archive ?
In vitro proteinase production by oral Candida albicans isolates from individuals with and without HIV infection and its attenuation by antimycotic agents. J Med Microbiol 1996; 44:311-6.
Long courses of oral or vaginal antimycotic agents can be effective treatment for recurrent Candida vulvovaginitis.
Effective management of Candida infection depends on accurate diagnosis; selection and administration of specific therapy and good compliance of the patient.3 There are variety of local and systemic antimycotic agents available for the treatment of vulvovaginal candidiasis.4 The systemic drugs are more expensive than topical preparations, but the latter can cause irritant contact dermatitis and are sometimes messy.
(9.) Ellepola AN, Samaranayake LP, Antimycotic agents in oral cxandidosis: an overview; 2.