Aspalathin has antimutagenic
properties and is exclusively found in rooibos, while nothofagin occurs elsewhere only in a red beech tree endemic to New Zealand.
In addition to antimicrobial, antineoplastic, antimutagenic
, and antioxidant effects, it is also effective in wound healing (5,15,16).
The mechanisms suggested for anticancer effect of honey include interference with multiple cell-signaling pathways, such as antiproliferative (Pichichero et al., 2010), inducing apoptosis (Jaganathan and Mandal, 2010), antimutagenic
(Saxena et al., 2012), and anti-inflammatory pathways (Hussein et al., 2012).
Evidence from animal in vitro and in vivo research indicates that saffron has potential anticarcinogenic, antimutagenic
, antioxidant, antidepressant and memory-enhancing properties.
Antioxidant properties (using chemical models and ex vivo lipoprotein studies), vase-dilating and lipid reduction properties, antimutagenic
effects (depending on used model), anti-glycation effects, and weight reduction properties (2-9) have been reported.
Beneficial results in terms of exhibiting significant antimutagenic
activity against colon cancer were also reported by Marotta et al.
So, Plumeria species are rich with various class of iridoids, and ridoids have versatile pharmaceutical activities including analgesic, anticoagulant, antihepatotoxic, antimutagenic
, antiprotozoal, antispasmodic, choleretic, hypoglycemic and immunomodulator activities [22-24].
Antioxidant and antimutagenic
activity of Carum copticum fruit extracts.
as a potential antioxidant and antimutagenic
These compounds possess numerous health-related effects such as antibacterial, antimutagenic
, anticarcinogenic, antithrombotic and vasodilatory activities (Bidlack et al, 2000) (3).
Several studies have shown that essential oil from turmeric has significant biological activities including antifungal, insect repellent, antibacterial, antimutagenic
, anticarcinogenic, antioxidant, anti-inflammatory, and antinociceptive properties [13-15].
Additionally, plants can play an important role in health because they may possess antimutagenic
and anticarcinogenic properties and contribute to immune system activation and protection against cardiovascular disease .