Protoanemonin, an antimutagen
isolated from plants.
Testing of pure compounds at doses relevant to their levels in tea identified epigallocatechin (EGC) and epigalocatechin-3-gallate (EGCG) as the primary antimutagens
. Studies of the inhibitory mechanisms established that the rate of degradation of N-hydroxy-IQ under aqueous conditions was not increased significantly in the presence of tea, in contrast to the results obtained with the complexing agent chlorophyllin (CHL), which rapidly degraded the mutagen.
Nagabhusan M, Amonkar AJ, Nair UJ Santhanam U, Ammigan N, D'Souza AV, Bhide SV (1988) Catechin as an antimutagen
: its mode of action.
Previously, it has been demonstrated that human diet contains many antimutagens
from Momordica charantia," Mutation Research, vol.
Activity profiles of antimutagens
: in vitro and in vivo data.
Recently, natural plants have received much attention as sources of biologically active substances including antioxidants, antimicrobials, antimutagens
and anticarcinogens nutraceuticals.
Fenwick In Dietary Anticarcinogens and Antimutagens
Chemical and Biological Aspects The Royal Society of Chemistry Cambridge p.
Therefore, agents which can protect cellular membranes against IR and ROS/RNS will have potential benefits as radioprotectors, antioxidant and antimutagens
(Odin 1997; Stavric 1994).
The use of antimutagens
and anticarcinogens in everyday life is the most effective procedure for preventing human cancer and genetic ailment.
It is known that, in general, green plants are a primary source of antimutagens
as well as natural toxic agents , and many plants contain cytotoxic and genotoxic substances resulting from the long-term use of such plants.
In vivo effects of single or combined dietary antimutagens
on mutagen-induced chromosomal aberrations.