antimuscarinics


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antimuscarinics

Drugs used to treat reversible airway obstruction as in ASTHMA and chronic BRONCHITIS. Examples are ipratropium bromide (Atrovent), oxitropium (Oxivent) and tiotropium (Spiriva).
References in periodicals archive ?
data for combinations of mirabegron with antimuscarinics or the use of 2 or more different antimuscarinics were not captured).
If a first antimuscarinic medication doesn't work or causes unacceptable side effects, modify the dose or offer a different antimuscarinic or beta3-adrenoceptor agonist, the guideline states.
Oral antimuscarinics are effective in reducing frequency, urgency, and incontinence.
Antimuscarinics work by binding to muscarinic receptors in the bladder and inhibiting involuntary bladder contractions.
These side effects are one major reason that patients stop OAB antimuscarinic medications.
Efficacy of mirabegron in patients with and without prior antimuscarinic therapy for overactive bladder (OAB): Post-hoc analysis of a prospective, randomised European-Australian phase III trial.
These drugs are also antimuscarinics, intended to relax the smooth muscle of the bladder.
Poor understanding of the disorder and limited treatment options means that many physicians have resorted to using antimuscarinics despite their limited proven efficacy in treating the pain.
In this survey of 519 physicians, (regarding 5,316 patients), pooled data across France, Germany, Spain and the UK found that the most common reason for switching antimuscarinics was lack of efficacy alone, accounting for 36% of 1,067 patients who switched therapy.
The major benefit of mirabegron is its lack of antimuscarinic side effects.