antimitotic agent


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antimitotic agent

Oncology
An agent that inhibits cancer growth by inhibiting cell division.
 
Pharmacology
A drug that inhibits or blocks mitosis in a particular phase of the cell cycle (e.g., metaphase arrest caused by colchicine and vinca alkaloids).

antimitotic agent

Antimicrotubule agent, mitotic inhibitor Oncology An agent that inhibits cancer growth by stopping cell division Pharmacology A drug that inhibits or blocks mitosis in a particular phase of the cell cycle–eg, metaphase arrest caused by colchicine and vinca alkaloids. See Chemotherapy.
References in periodicals archive ?
Noker, "Antimitotic agents: structure-activity studies with some pyridine derivatives," Journal of Medicinal Chemistry, vol.
Synthetic benzophenones, for instance, dihydroxy-4-methoxy benzophenone [2], and 2-aminobenzophenone [3] have turned out to be anticancer and antimitotic agents, respectively.
Synthesis of a new 4-aza2,3-didehydropodophyllotoxin analogues as potent cytotoxic and antimitotic agents. Bioorganic and Medicinal Chemistry 19, 2349-2358.
They act as antimitotic agents in the epidermis by influencing gene transcription resulting in inhibition of the immunological, inflammatory and proliferative processes of the disease [14-16].
An Aden carcinoma is involved in the majority of such cases, but in most cases it is actually the antimitotic agents that are at fault (mitomycin C, 5-fluorouracil, platinum-based drugs and bleomycin).