antimitotic agent


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antimitotic agent

Oncology
An agent that inhibits cancer growth by inhibiting cell division.
 
Pharmacology
A drug that inhibits or blocks mitosis in a particular phase of the cell cycle (e.g., metaphase arrest caused by colchicine and vinca alkaloids).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

antimitotic agent

Antimicrotubule agent, mitotic inhibitor Oncology An agent that inhibits cancer growth by stopping cell division Pharmacology A drug that inhibits or blocks mitosis in a particular phase of the cell cycle–eg, metaphase arrest caused by colchicine and vinca alkaloids. See Chemotherapy.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Noker, "Antimitotic agents: structure-activity studies with some pyridine derivatives," Journal of Medicinal Chemistry, vol.
Synthetic benzophenones, for instance, dihydroxy-4-methoxy benzophenone [2], and 2-aminobenzophenone [3] have turned out to be anticancer and antimitotic agents, respectively.
Synthesis of a new 4-aza2,3-didehydropodophyllotoxin analogues as potent cytotoxic and antimitotic agents. Bioorganic and Medicinal Chemistry 19, 2349-2358.
They act as antimitotic agents in the epidermis by influencing gene transcription resulting in inhibition of the immunological, inflammatory and proliferative processes of the disease [14-16].
An Aden carcinoma is involved in the majority of such cases, but in most cases it is actually the antimitotic agents that are at fault (mitomycin C, 5-fluorouracil, platinum-based drugs and bleomycin).