antimetabolite agents

antimetabolite agents

intravenous or topical drugs used in the treatment of neoplasms and to suppress psoriasis, e.g. methotrexate, fluorouracil
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5-flurouracil (5-FU) is a chemotherapeutic drug which comes under the category of antimetabolite agents or pyrimidine analogs, commonly used in the treatment of gastrointestinal tract carcinomas (CA), breast cancer, head and neck, cervical CA, etc.
Folic acid supplementation is specifically contraindicated with many antimetabolite agents and so should be avoided.