antimalarials


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antimalarials

Drugs used to prevent and treat MALARIA. They include chloroquine (Avloclor), dapsone, pyrimethamine (Daraprim), mefloquine (Lariam), atovaquone with proguanil hydrochloride (Malarone), proguanil (Paludrine) and artemether with lumefantrine (Riamet).
References in periodicals archive ?
There is no room for complacency and people really must visit their GP, pharmacy, practice nurse or travel clinic before they leave to discuss prevention and the best choice of antimalarial for their trip.
The sustainable supply and rational use of effective antimalarials is required both for clinical cure and for reduction in malaria transmission.
However, sporadic reports have shown some antimalarial therapeutic effect when administered to patients with clinical manifestations of malaria.
Monitoring drug efficacy, safety, quality of antimalarials is ongoing, as is discouraging monotherapy use of these agents.
Currently, treatment for malaria combines rapidly-acting artemisinins with lumefantrine, amodiaquine, mefloquine and other antimalarials for durability.
Isoquine and related amodiaquine analogues: A new generation of improved 4-aminoquinoline antimalarials.
Patients with localized CLE can do reasonably well with sun protection and topical and intralesional treatments, but patients with more extensive disease typically need systemic treatment, most often with antimalarials, she noted.
This lead to develop more active antimalarials and hence plasmepsins that is in the genome of malarial parasite, was made a target and inhibition of Plasmepsins provided a significant way to control wide spreading malaria [24-29].
Because blood smear microscopy was not done, it was not known whether the patient had hyperparasitemia (>5% parasitemia), which is one sign of severe malaria, and for which parenteral antimalarials are indicated.
Amongst 18 deaths, seven patients had received antimalarials before onset of breathlessness (39%), whereas amongst survived patients six had received antimalarials before onset of breathlessness (50%).
The Central Council for Research in Ayurveda, Homoeopathy, Unani under Department of Ayush has also patented and commercialised an antimalarial drug AYUSH 64," said Dr Harsh Vardhan.