antimalarial


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Related to antimalarial: Antimalarial Drugs

antimalarial

 [an″te-, an″ti-mah-lar´e-al]
therapeutically effective against malaria.
antimalarial agent.

an·ti·ma·lar·i·al

(an'tē-mă-lā'rē-ăl),
1. Preventing or curing malaria.
2. A chemotherapeutic agent that inhibits or destroys malarial parasites.

antimalarial

/an·ti·ma·lar·i·al/ (-mah-lar´e-al) therapeutically effective against malaria, or an agent with this quality.

antimalarial

(ăn′tē-mə-lâr′ē-əl, ăn′tī-)
adj.
Preventing or treating malaria.
n.
A drug used to prevent or treat malaria.

antimalarial

[-məler′ē·əl]
1 pertaining to a substance that destroys or suppresses the development of malaria plasmodia or to a procedure that exterminates the mosquito vectors of the disease, such as spraying insecticides or draining swamps.
2 an antimalarial drug. Chloroquine and hydroxychloroquine sulfate are effective against Plasmodium vivax, P. malariae, and certain strains of P. falciparum. Patients with drug-resistant P. falciparum are often treated with a combination of quinine, pyrimethamine, and sulfadoxine.

an·ti·ma·lar·i·al

(an'tē-mă-lārē-ăl)
1. Preventing or curing malaria.
2. A chemotherapeutic agent that inhibits or destroys malarial parasites.

antimalarial

1. Effective in the treatment or prevention of malaria.
2. An antimalarial drug.
References in periodicals archive ?
Verbaanderd continued that the results lead them to believe that these antimalarial drugs could offer significant clinical benefit for certain cancer patients, especially in combination with standard anticancer treatments.
The partnership between MMV and Novartis builds on a long-standing successful collaboration in antimalarial drug development, which led to the launch in 2009 of the first high-quality artemisinin combination therapy for children.
We are very encouraged by the favorable progress of our collaboration with the Broad Institute and are hopeful that it will lead to a new antimalarial medicine that will benefit the millions currently in need," said Haruo Naito, CEO of Eisai Co.
Introduction of Antimalarial Drugs with the Quinoline Scaffold
4 ) and further examined for antimalarial (plamepsin inhibition)and analgesic responses.
5%) into 96-well plates predosed with antimalarial drugs (monodesethylamodiaquine, lumefantrine, chloroquine, quinine, mefloquine, dihydroartemisinin, artesunate, piperaquine, pyronaridine, and doxycycline).
Bhatia infected the iPSC-derived hepatocytes with parasitic plasmodium species, characterized the cells' drug metabolism capabilities using known antimalarial drugs, and chemically matured the cells to demonstrate higher sensitivity to a different class of drugs.
Following data were noted in each case: the demographic profile of these patients; reports of peripheral smear, malarial antigen test, ABG analysis, chest radiograph findings; whether antimalarial therapy was started before the onset of breathlessness; therapeutic intervention in the form of high flow oxygen or invasive or non-invasive ventilation, antimalarials used; other complications associated with malaria like anaemia, thrombocytopenia, acute kidney injury, hepatic involvement, shock and cerebral involvement; comorbid conditions like diabetes mellitus, hypertension, asthma, chronic obstructive pulmonary disease (COPD), ischemic heart disease, HIV infection; ventilator associated complications and death or survival.
Various in silico therapeutic calculations for novel antimalarial compound and pyrimethamine were executed using computational approaches.
The report's authors cite the importance of incremental innovation in the development of AIDS, oncology and antimalarial therapies.
Thus, a complex of antimalarial activities allowed to interrupt local transmission of malaria within the country.
1-3] Malaria case management encompasses prompt and effective treatment to minimise morbidity and mortality, reduce transmission and prevent the emergence and spread of antimalarial drug resistance.