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antigen-presenting cellAbbreviation: APC
A cell that breaks down antigens and displays their fragments on surface receptors next to major histocompatibility complex molecules. This presentation is necessary for some T lymphocytes that are unable to recognize soluble antigens. Macrophages are the primary antigen-presenting cells, but B cells and dendritic cells also can act as APCs.See: T cell; macrophage processing cell
See also: cell
Medical Dictionary, © 2009 Farlex and Partners
antigen-presenting cellA cell, such as a macrophage, a B cell or a dendritic cell, that presents processed antigenic peptides and MHC class II molecules to the T cell receptor on CD4 T cells.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005