antigen receptor


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Related to antigen receptor: monoclonal antibody

antigen receptor

Receptors, primarily on white blood cells, that bind with the epitope on foreign antigens, stimulating an immune response.
See: epitope
See also: receptor
References in periodicals archive ?
5 December 2015) Characterization and Accurate Early Prediction of Cytokine Release Syndrome After Chimeric Antigen Receptor (CAR) T cell Therapy for Acute Lymphoblastic Leukemia (ALL) [poster presentation].
DelveInsight is offering the Report on Chimeric Antigen Receptor (CAR)-T cell Immunotherapy at a price of USD 1,750 as a single user license, USD 3,500 as a site license and USD 5,000 as a Global/Enterprise License.
The utility of the polymerase chain reaction as a screening method for the detection of antigen receptor gene rearrangements.
Sustained Remissions Following Chimeric Antigen Receptor Modified T Cells Directed Against CD19 (CTL019) in Patients with Relapsed or Refractory CD19+ Lymphomas [oral presentation].
Cell-based cancer immunotherapies are based on chimeric antigen receptor, or CAR, and high-affinity T cell receptor, or TCR, approaches to genetically engineer T cells to recognize and kill cancer cells.
Researchers determined that infusing a transplant donor's T-cells that have been genetically modified to express a chimeric antigen receptor (CAR) targeting an antigen known as CD19 can induce complete or partial remission of certain blood cancers in patients who have previously received an allogeneic hematopoietic stem cell transplantation (alloHSCT).
Global & USA Cancer Immunotherapy Market Analysis To 2020 : Antibody Drug Conjugates (ADCs), Bispecific Monoclonal Antibodies, Cancer Vaccines, Cytokines, Interferons, Chimeric Antigen Receptor (CAR) T-Cell Therapy, PD-1/PD-L1 inhibitors, Dendritic Cells, Checkpoint Inhibitors, Adopted Cell Therapy (ACT) & IDO Inhibitors
Cathepsin S has been highly associated with the processing and activation of the antigen receptor called MHC-II, essential for the initiation of both normal and pathological immune responses mediated by T-cells.
Engineered Donor T Cells May Eradicate Progressive Disease After Stem Cell Transplant Allogeneic T-Cells Expressing an Anti-CD19 Chimeric Antigen Receptor Cause Remissions of B-Cell Malignancies after Allogeneic Hematopoietic Stem Cell Transplantation without Causing Graft-Versus-Host Disease [99]
DSBs are cytotoxic DNA lesions that arise as a by-product of DNA replication, but also as a physiological intermediate during antigen receptor diversification in the Immune system.
Novartis and the University of Pennsylvania's Perelman School of Medicine (Penn) have an exclusive global collaboration to research, develop and commercialize chimeric antigen receptor (CAR) T cell therapies for the investigational treatment of cancers.
That work, which culminated in papers published in The New England Journal of Medicine in 2013, showed that various forms of lymphoma respond well to treatment with ibrutinib (trade name Imbruvica) or idelalisib (trade name Zydelig), two drugs that precisely target the B-cell antigen receptor, a protein found in white blood cells.