antigen receptor


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Related to antigen receptor: monoclonal antibody

antigen receptor

Receptors, primarily on white blood cells, that bind with the epitope on foreign antigens, stimulating an immune response.
See: epitope
See also: receptor
References in periodicals archive ?
Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma," Molecular Therapy, vol.
DelveInsight Report, "PD-1 and PD-L1 inhibitors and Chimeric Antigen Receptor (CAR)-T cell Immunotherapy - Competitive Landscape, Pipeline and Market Analysis, 2015" gives the comprehensive insights on the PD-1 and PD-L1 Inhibitors and CART Immunotherapy.
CBMG) and GE Healthcare Life Sciences China have established a strategic research collaboration to develop certain high-quality industrial control processes in Chimeric Antigen Receptor T-cell (CAR-T) and stem cell manufacturing.
The company's lead product candidate, axicabtagene ciloleucel, is an investigational therapy in which a patient's T cells are engineered to express a chimeric antigen receptor to target the antigen CD19, a protein expressed on the cell surface of B-cell lymphomas and leukemias, and redirect the T cells to kill cancer cells.
com)-- DelveInsight, the leading Business Consultant and Market Research firm is pleased to declare the launch of its report, Chimeric Antigen Receptor (CAR)-T cell Immunotherapy- Competitive Landscape, Technology and Pipeline Analysis, 2015.
Hematologists, oncologists, pediatricians, and other clinicians from North America, Asia, and France cover the history of its treatment, its epidemiology and etiology, diagnosis and classification, molecular pathogenesis, cytogenetics, chemotherapy for adults and children, the use of asparaginase, the monitoring of minimal residual disease to guide therapy, prophylaxis and treatment of central nervous system involvement, pharmacogenomics and chemotherapy, hematopoietic stem cell transplantation, long-term complications of therapy, and new treatment agents, including bispecific T-cell engaging antibodies and autologous antigen receptor expressing T-cells.
Cathepsin S has been highly associated with the processing and activation of the antigen receptor called MHC-II, essential for the initiation of both normal and pathological immune responses mediated by T-cells.
If approved by the FDA and EMA, Kymriah would represent the first chimeric antigen receptor T cell therapy available for two distinct indications in non-Hodgkin lymphoma and B-cell ALL.
NASDAQ: ITUS) has entered into a Cooperative Research and Development Agreement (CRADA) with Tampa, Florida-based cancer prevention-focused Moffitt Cancer Center to advance a chimeric antigen receptor T-cell (CAR-T) technology toward human clinical testing, the company said.
It utilises the -1BB costimulatory domain in its chimeric antigen receptor to increase cellular expansion and persistence.
OTCQB: IMUN) has signed a binding letter of intent to acquire Chinese Chimeric Super Antigen Receptor T cell (CAR-T) cocktail therapy, Immuno-Oncology patents (pending), manufacturing technology, and clinical data of the aforementioned therapies from newly-formed Chinese biotech firm Super-T Cell Cancer Co, the company said.
Additionally, Lilly will make a $30 million equity investment in BioNTech's subsidiary, Cell & Gene Therapies GmbH, which specializes inTCR and chimeric antigen receptor immunotherapeutics.