antigen processing


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antigen processing

the steps that occur in an immune response after a protein is recognized as foreign.

antigen processing

The mechanism by which foreign antigens are taken into antigen-presenting cells (APCs) and broken up. Part of the antigen is then displayed (presented) on the surface of the APC next to a histocompatibility or self-antigen, activating T lymphocytes and cell-mediated immunity. T lymphocytes are unable to recognize or respond to most antigens without APC assistance.
See: antigen; macrophage processing; self
See also: processing
References in periodicals archive ?
If there is an adverse indirect effect on cell-mediated immunity due to PRN exposure, it could result from altered antigen processing and presentation characteristics of the APC.
The discovery engine selects Apitopes - Antigen Processing Independent epiTOPES.
Factoring in antigen processing in designing anti-tumor T-cell vaccines, Lvy, Colombetti, Janda, Chapatte, Alves, Casado, Lvy and Peitrequin 2.
The assay identifies antigens that are displayed to T cells by Class II HLA molecules on dendritic cells, which is the most direct way for measuring antigen processing and presentation.
The proteasome is involved in many essential cellular functions, such as regulation of cell cycle, cell differentiation, signal transduction pathways, antigen processing for appropriate immune responses, stress signaling, inflammatory responses, and apoptosis.
First, Select VLPs have a specific size and assembly process different from other VLPs which enables the expression of much larger vaccine antigens than can be expressed on other types of VLPs and also offers the prospect for distinctive antigen processing.