Thus, if PRN exposure only partially interferes with antigen processing or presentation, its adverse effect may be masked under these in vitro assay conditions.
Antigen processing: where tumor-specific T-cell responses begin.
Such a low T-cell epitope discovery rate is due to the fact that we do not have adequate models for predicting antigen processing yet .
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HLA class I polymorphisms primarily concentrated in the peptide binding region (PBR) not only influence the features and repertoire of peptides presented to the cell surface but also affect their requirement on the PLC components for antigen processing and presentation [15-19].
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