interferon gamma

(redirected from antigen interferon)
Also found in: Dictionary.

in·ter·fer·on gam·ma

interferon elaborated by T lymphocytes in response to either specific antigen or mitogenic stimulation; only one gene codes for gamma interferon. interferon γ behaves like a biologic response modifies and is highly immunoregulatory.
Farlex Partner Medical Dictionary © Farlex 2012

interferon gamma

The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

IFNG

A gene on chromosome 12q14 that encodes a soluble cytokine belonging to the type-II interferon family that has antiviral, immunoregulatory and anti-tumour properties, and is a potent macrophage activator. It is produced by lymphocytes activated by specific antigens or mitogens.

Molecular pathology
Defects in IFNG is associated with increased susceptibility to aplastic anaemia in Caucasians.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

interferon gamma

IFN-γ A 21-25 kD glycoprotein lymphokine encoded on chromosome 12q and produced by activated T and NK cells; IFN-γ is antiviral, regulates class II MHC antigen expression, Fc receptors and immunoglobulin production and class switching, activates monocyte cytotoxicity and enhances NK cell activity; IFN-γ is ↓ in IgA deficiency, lymphoma, CLL, infections–eg, CMV, EBV, rubella, lepromatous leprosy, TB, SLE, rheumatoid arthritis, sickle cell anemia, post-transplantation Indications Recombinant IFN-γ is used to treat condylomata acuminata, CLL, Hodgkin's disease, mycosis fungoides, rheumatoid arthritis, and possibly leprosy, TB, nontuberculous mycobacterial infections, toxoplasmosis, chronic granulomatous disease–to prevent infections; IFN-γ suppresses collagen synthesis by fibroblasts, ↓ the size of keloids, causing a local ↑ in inflammatory cells and mucin production, and may be of use in controlling abnormal fibrosing conditions Side effects Acute renal failure, rash, headache, chills
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

in·ter·fer·on gam·ma

(intĕr-fēron gamă)
That interferon elaborated by T lymphocytes in response to either specific antigen or mitogenic stimulation.
Synonym(s): antigen interferon, immune interferon.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

interferon gamma

An INTERFERON used as an antiviral drug. A brand name is Immukin.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

in·ter·fer·on gam·ma

(intĕr-fēron gamă)
Interferon elaborated by T lymphocytes in response to either specific antigen or mitogenic stimulation.
Medical Dictionary for the Dental Professions © Farlex 2012