antifreeze

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antifreeze

A fluid with a high concentration of ethylene glycol or methanol, which is added to car, truck and other cooling systems for internal combustion engines to substantially reduce the freezing point of the coolant.

Antifreeze has long had currency as a surrogate inebriant despite it being associated with acidosis and renal shutdown (due to ethylene glycol), as well as blindness (due to methanol).

Clinical findings
In low amounts, antifreeze simulates alcohol metabolism; at high levels, it is associated with nausea, vomiting, seizures, coma or death (at levels above 100 ml of ethylene glycol).

antifreeze

Toxicology A fluid with a high concentration of ethylene glycol or methanol, which is added to car, truck, and other cooling systems for internal combustion engines to substantially ↓ the freezing point of the coolant; antifreeze has long had currency as a surrogate inebriant, despite its being associated with acidosis and renal shutdown–ethylene glycol and blindness–methanol Clinical In low amounts, antifreeze simulates alcohol metabolism; at high levels, it is associated with N&V, seizures, coma, death, at levels above 100 ml of ethylene glycol. See Leukovorin rescue. Methotrexatre

antifreeze

see ethylene glycol.
References in periodicals archive ?
However, the antifreeze liquids were recycled, only replacing that absorbed by the catch with an amount sufficient to maintain levels at 300 mL.
In accordance with prior experience, both antifreeze formulations captured far more flies than those with water/surfactant as the capture liquid.
Because the additives in antifreeze are proprietary the material safety data sheets provided by the manufacturer list only those compounds which are considered to be significant safety hazards when used in accordance with the manufacturer's recommendations.
Based on industry-wide practices, the other additives include, but are not limited to: sodium silicate, disodium phosphate, sodium molybdate, sodium borate, dextrin (hydroxyethyl starch), and a green dye, disodium fluorescein (dyes are added to antifreeze to help trace the source of leaks, and as an identifier because the different formulations are incompatible).
The characteristic odor in the automotive antifreeze formulation is caused by the tolytriazole.
We have solved the structure for fish antifreeze, so we know how it binds to ice, but it doesn't mean that the insect ones will bind in the same manner.
Grown with the budworm protein, however, the ice crystals look like smooth, hexagonal disks, which would cause less damage to cells preserved with antifreeze, he suggests.
Recently, researchers interested in crystal growth in general have started to take a closer look at the action of antifreeze proteins.
provide important hints about how antifreeze proteins may prevent crystals from growing.
Instead, its effectiveness peaks when antifreeze levels reach about 4 percent by weight.
The adsorption of antifreeze glycoproteins on an ice surface, says biochemist Robert E.