antifreeze


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antifreeze

A fluid with a high concentration of ethylene glycol or methanol, which is added to car, truck and other cooling systems for internal combustion engines to substantially reduce the freezing point of the coolant.

Antifreeze has long had currency as a surrogate inebriant despite it being associated with acidosis and renal shutdown (due to ethylene glycol), as well as blindness (due to methanol).

Clinical findings
In low amounts, antifreeze simulates alcohol metabolism; at high levels, it is associated with nausea, vomiting, seizures, coma or death (at levels above 100 ml of ethylene glycol).

antifreeze

Toxicology A fluid with a high concentration of ethylene glycol or methanol, which is added to car, truck, and other cooling systems for internal combustion engines to substantially ↓ the freezing point of the coolant; antifreeze has long had currency as a surrogate inebriant, despite its being associated with acidosis and renal shutdown–ethylene glycol and blindness–methanol Clinical In low amounts, antifreeze simulates alcohol metabolism; at high levels, it is associated with N&V, seizures, coma, death, at levels above 100 ml of ethylene glycol. See Leukovorin rescue. Methotrexatre
References in periodicals archive ?
The report of global Antifreeze Proteins (AFP) market includes the competitive landscape section which provides the full and in-depth analysis of the current market trends, changing technologies and developments that will be beneficial for the companies, which are competing in the market.
This is one misconception about NRC Alaska's antifreeze products that Rose encounters; a second and closely related one is that products made with recycled glycol are low quality.
RSPCA Inspector Kate Levesley antifreeze poisonings in the area, we would urge all cat-owners to keep a close eye on their pets and their behaviour and if they suspect they have been poisoned we would advise they seek immediate veterinary attention."
Saying Sooty "wasn't a nuisance cat - far from it" - she added: "Apparently the smell and taste of antifreeze is attractive to cats because it's quite sweet.
They believe he has been poisoned, possibly by antifreeze, and he is in a bad way.
Cats are thought to enjoy the sweet taste of the antifreeze, but it can quickly cause fatal kidney failure.
"It is thought that this is due to an increased trend for the use of antifreeze in garden water features from which many cats drink freely."
Colorless, odorless ethylene glycol in antifreeze is highly poisonous to dogs, cats and humans.
If you suspect your pet has ingested antifreeze, contact your vet immediately.
Each year, up to 90,000 pets are poisoned by ingesting antifreeze that drips onto our garage floors and driveways, or is left in open containers.
It is vital that consumers continue to read the labels and follow label instructions on the proper use, storage and disposal of antifreeze. Today, all major marketers are placing the bitterant in antifreeze in all 50 states," said Phil Klein, executive vice president, legislative and public affairs for CSPA.
Deval Patrick on Friday signed "Schubert's Law," which mandates the addition of a bittering agent to large wholesale containers of antifreeze so pets and children won't be attracted to the poisonous sweet-tasting substance.