1. Antagonistic to the action of folic acid.
See also: folic acid antagonists.
2. Any agent with this effect.
See also: folic acid antagonists.
References in periodicals archive ?
The major commercial application of this enzyme is in the hydrolysis of gallotannin to gallic acid, which is an intermediate required for the synthesis of an antifolic antibacterial drug trimethoprim (Sitting et al.
Cross-resistant and collateral susceptibility to antifolic antimalarial compounds.