antifilarial

antifilarial

 
1. destructive to filariae.
2. an agent having this effect.

antifilarial

1 pertaining to a substance or agent destructive to filariae.
2 an antifilarial agent.
References in periodicals archive ?
DEC has been used as an antifilarial drug since 1947.
perstans nematodes raises questions about treatment (1) because of poor responses to standard antifilarial drugs and limited findings from controlled trials.
Ivermectin, an antifilarial drug, is the essential tool in eradicating river blindness from the developing world.
Improved canine chemoprophylaxis may require combinations or sequential dosages of the macrocyclic lactones including ivermectin, moxidectin, selamectin, and milbemycin oxime; or by adding another effective antifilarial medication, such as melarsomine dihydrochloride to the prophylactic regimen.
The present study has identified Sd30 (Sd--Setaria digitata, 30-MW-30 kDa), an allergenic fraction purified from Setaria digitata (a cattle filarial parasite) that can detect the antifilarial (Wuchereria bancrofti) antibodies (IgM and IgG4) produced during the acute/chronic manifestation of extra lymphatic pathology like arthritis caused by W.
3% recurrence of lymphedema, which the authors attributed to discontinuation of antifilarial drugs.
Chalcones (1,3-diphenyl-2-propen-1-ones) [1] are known to possess a range of important biological activities, such as antibacterial [2], antifungal [3], antileishmanial [4], antimalarial [4], antifilarial [5] anti-inflammatory [6-8], antiprotozoal (antileishmanial and antipanosomal) [9], antimicrobial [10-13], larvicidal [14], anticonvulsant [15], anti-HIV [16], antitumor [17], and anticancer [18] activities, and they could be readily transformed into varieties of other compounds, many of which are biologically active heterocycles [19, 20].
In that work, he and his colleagues evaluated the safety and efficacy of administered annual antifilarial drugs over five years to residents of five villages in Papua New Guinea.
Under this programme, a single-dose antifilarial drug DEC is administered in the dose of 6 mg/kg of body-weight to inhabitants in filaria-endemic areas, excluding children below 2 years of age, pregnant women, and seriously-ill persons.
With elimination targeted for 2020, the Global Programme to Eliminate Lymphatic Filariasis, begun in 2000, has delivered approximately 3 billion courses of antifilarial treatment at a cost of $0.