antifibrotics

antifibrotics

Drugs used to treat disorders due to abnormal scar formation such as PEYRONIE'S DISEASE or SCLERODERMA. An example is potassium para-aminobenzoate (Potaba).
References in periodicals archive ?
Antifibrotics and wound healing in glaucoma surgery.
Purified triamcinolone acetonide as antifibrotic adjunct in glaucoma filtering surgery.
The authors suggested that the improvement in eGFR may have been due to a reduction in fibrosis and that antifibrotics may be able to halt and potentially reverse a degree of renal injury.
Tranilast is another antifibrotic agent thought to interfere with the effects of TGF-[beta].
Silymarin is the main active component found in seeds of milk thistle and has been used since ancient times for a variety of ailments; it is thought to have powerful anti-inflammatory, antioxidant, and antifibrotic properties [171].
"The Role of Antifibrotics in Prevention of Laminectomy Scar" Wayne H.
These topics included toxicology without animal testing (Tox21 program), human lung cultures, alternatives to fetal bovine serum, recombinant antibodies, in vitro systems for testing antifibrotic agents, and microphysiological systems in applied research (organ-on-achip systems).
Antifibrotic agents are important for wound healing and scar formation.
Antifibrotic effects of mitomycin C have been reported in in vitro and in vivo studies (KUNITOMO & MORI, 1969; YAMAMOTO et al., 1990).
Despite the good results confirmed by many researchers, there have been some controversies about the efficacy of mitomycin C as an antifibrotic agent (BROOKS et al., 1996; MINGUINI et al., 2000).
This study was carried out to evaluate the antifibrotic effect of ethanol extract of the fruits of Indian herb Piper longum Linn.
Keywords: Hepatic fibrosis; C[Cl.sub.4]; Antifibrotic effect; Piper longum Linn.