antifibrinolysis

antifibrinolysis

The prevention of the breakdown of fibrin which is a major element in the formation of a blood clot. Drugs such as aminocaproic acid and tranexamic acid inhibit fibrinolysis.
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Our preoperative deliberations focused on options for vascular access (peripheral versus central; standard peripheral IV versus rapid infusion catheter; multilumen central venous access versus large-bore introducer), blood pressure monitoring (noninvasive versus intraarterial; radial versus femoral arterial), anaesthetic approach (general versus spinal versus epidural anaesthesia), neuraxial anaesthetic technique (single injection versus continuous administration of local anaesthetic), blood management (type of blood products; intraoperative cell salvage), and coagulation (antifibrinolysis).
[3] Antifibrinolysis and haemostasis are the two mechanisms, which can be used for optimal surgical field without endangering life or well-being of the patient.