adjective Referring to an effect that suppresses or inhibits oestrogenic activity.
noun An agent that counters oestrogenic activity.


adjective Referring to an effect that suppresses or inhibits estrogenic activity noun A general term for an agent that counters estrogenic activity


Counteracting or suppressing estrogenic activity.
Synonym(s): antioestrogenic.
References in periodicals archive ?
3,3'-diindolylmethane (DIM) is a compound found in cruciferous vegetables that has been well studied in breast, cervical, and thyroid cancers for its antiestrogenic, positive estrogen metabolism effects.
Evaluation of estrogenic, antiestrogenic and genotoxic activity of nemorosone, the major compound found in brown Cuban propolis.
Letrozole as an aromatase inhibitor induces ovulation in women with PCOS without having antiestrogenic effects on the endometrium (10).
The randomized, double-blind, phase II study compared transdermal application of a gel containing 4-hydroxytamoxifen (4-OHT), an antiestrogenic metabolite of tamoxifen (4 mg/day), to oral tamoxifen (20 mg/day) in preand postmenopausal women with estrogen receptor--positive ductal carcinoma in situ (DCIS).
4] and the use of adjuvant hormone therapy with antiestrogenic agents, such as tamoxifen, to reduce the risk of recurrence.
The objective of this study was to investigate the antiestrogenic activity of 3,3'-diindolylmethane (DIM), a bioactive compound derived from cruciferous vegetables, in patients with TPD.
Despite the fact that CSCs are not known to be ER positive, breast cancers have been successfully treated with antiestrogenic therapy only.
Of all the isoflavones, genistein is still attracting the most attention because of its estrogenic and antiestrogenic effects which, at high concentration, have shown inhibition on cancer cell lines through the modulation of the transforming growth factor (TGF) (Kim 1998).
15) ER expression is strongly predictive of response to antiestrogenic therapy.
This difference suggests an antiestrogenic effect of smoking among postmenopausal women that may further reduce their already low endogenous estrogen levels.