ESAF showed a better anticonvulsant activity in the PTZ model than MES antiepileptic
All patients of either gender aged below 18 years, diagnosed with epilepsy and with no change in antiepileptic
drug therapy in the last 3 months, attending the outpatient Departments of Medicine, Neurology, inpatients of medical wards, or those presenting to the emergency room of a tertiary care hospital were not recruited.
Either newly diagnosed cases of generalized epilepsy without antiepileptic
treatment or known cases of generalized epilepsy on carbamazepine monotherapy were included in the study along with the age and gender matched healthy subjects as controls.
Herzog and his associates examined the frequencies of seizure outcomes on hormonal and nonhormonal contraceptives stratifying by type of antiepileptic
drug women used when starting a particular contraceptive method.
drugs therapy in elderly requires pharmacokinetics and pharmacodynamic adjustment due to the physiological changes associated with aging and frequent co-morbid conditions.
Mothers who had epilepsy provided data about the use of antiepileptic
drugs during pregnancy and breastfeeding.
Fifty-three men treated with antiepileptic
drugs for at least two years prior to enrollment in the Anti-Epileptic Drug and Osteoporosis Prevention Trial (ADOPT) were randomized to receive risedronate (a drug that helps prevent fractures) or a placebo for 12 weeks.
Patients in the study who withdrew from antiepileptic
drug (AED) treatment were not significantly more likely to have seizure recurrence than were those who did not, thereby meeting the common secondary goal of discontinuing or reducing AEDs after epilepsy surgery Thus, the findings of this study may provide reassurance to neurologists who are hesitant to withdraw AEDs after surgery because of concerns that seizures may recur, Dr.
The IQs were compared to matched children who were not exposed to the antiepileptic
Since women in the study were taking antiepileptic
drugs throughout pregnancy, it is unclear whether the effects on IQ are related to the timing or duration of prenatal valproate exposure, so "exposure to valproate at any time during pregnancy should be considered to have the potential to result in decreased IQ in children," the advisory says.
announced today that it will launch antiepileptic
agent Inovelon(R) Tablets 100 mg and 200 mg (rufinamide) in Japan on May 29 as an adjunctive therapy to other antiepileptic
drugs (AEDs) in the treatment of Lennox-Gastaut syndrome (LGS).
SAN DIEGO--Women who were most likely to be on older antiepileptic
drugs were the least likely to be counseled about the dangers those drugs pose to bone health in a retrospective study of 756 women with epilepsy.