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An older group of antidepressants is the monoamine oxidase inhibitorsisocarboxazid (Marplan), phenelzine (Nardil), and tranylcypromine (Parnate). These drugs inhibit monoamine oxidase, the enzyme that breaks down norepinephrine and serotonin released at nerve synapses. They are not as widely used as the tricyclic antidepressants because serious cardiovascular side effects (hypertension, headache, stroke syndrome) can occur when tyramine is ingested, and foods containing tyramine, such as cheese, certain beans, beer, and wine, must be avoided by patients taking monoamine oxidase inhibitors.
A third class consists of the selective serotonin reuptake inhibitors, which inhibit reuptake of serotonin without affecting reuptake of norepinephrine. This group includes fluoxetine (Prozac), paroxetine (Paxil), and sertraline (Zoloft). Drugs in this group are as effective as the tricyclic antidepressants but have fewer side effects. The most significant adverse reaction seen with this group is agitation, which can be lessened by decreasing the dose. Weight gain and sexual dysfunction may also occur.
antidepressant/an·ti·de·pres·sant/ (an″te-) (an″ti-de-pres´ant) preventing or relieving depression; also, an agent that so acts.
antidepressantadjective Relieving depression noun An agent used to manage depression, anxiety, panic disorders. See Depression, Prozac/fluxetine, Tricyclic antidepressant.
antidepressantOne of the large range of drugs used to treat depression. Classes of antidepressant drugs include bicyclics, tricyclics, tetracyclics, monoamine oxidase inhibitors (MAOIs) and selective serotonin re-uptake inhibitors. Some of the most commonly used drugs are lithium (Camcolit), nortriptyline (Allegron), amoxapine (Asendis), citalopram (Cipramil), protriptyline (Concordin), flupenthixol (flupentixol) (Fluanxol), maprotiline (Ludiomil), tradozone (Molipaxin), fluphenazine (Modecate, Moditen), phenelzine (Nardil), tranylcypromine (Parnate), dothiepin (dosulepin) (Prothiaden), promazine (Sparine), thioridazine (Melleril), imipramine (Tofranil), perphenazine (Fentanyl), prochlorperazine (Stemetil), trifluoperazine (Stelazine), amitryptyline (Triptafen), clomipramine (Anafranil), doxepin (Sinequan), isocarboxazid (Marplan), tranylcypromine (Parnate), fluoxetine (Prozac) and tryptophan (Optimax).
antidepressanta drug counteracting depression; low-dosage tricyclic antidepressants (e.g. amitriptyline) may be used in the treatment of intractable pain states; major antidepressants, tricyclic antidepressants and monoamine oxidase inhibitors (MAOIs) contraindicate the administration of adrenalinized local anaesthetic solutions
Patient discussion about antidepressant
Q. My sister is taking antidepressants for her depression. My sister is taking antidepressants for her depression. Antidepressant causes her severe headache. Her medicines were changed but there is no impact in her headache. This headache is continuous and reduces only after a good sleep. I think she can try with Chinese medicines for her headache? Will it be of any help?
Q. Please suggest me the natural or alternative ways to beat depression without taking any antidepressants? I suffer from clinical depression yet never tried antidepressants due to the fear of getting addicted to them. Please suggest me the natural or alternative ways to beat depression without taking any antidepressants?
Q. I was diagnosed with depression and have taken a whole host of antidepressants. I’m Mark, 29 years old male. I was diagnosed with depression and have taken a whole host of antidepressants. My eyes are extremely blurry, I’m worrying about that. Does this side effect go away with time, or is it permanent while on medications?
Sometimes it does take many, many attempts to discover an anti-depressant or a combination of more than one to achieve a better mood balance. We're all chemically different and react to drugs differently. There's many options and I had to endure years of experimentation before I was satisfied, but I now have the rest of my life to appreciate what I went through.
I also used the help of different doctors and psychiatrists, as well as self-learning. If your doctor doesn't seem to be beneficial, consider asking him/her to recommend a specialist. New treatments come to light regularly and not all docotrs are wise to them.
Just yesterday (01.20.09) a new, control