Sommer, "Anticytokine therapy
in neuropathic pain management," Expert Review of Neurotherapeutics, vol.
Studies showed higher efficacy of anticytokine therapy
such as anti-IL-6 and anti-TNF.
is a powerful tool to fight autoimmune and autoinflammatory diseases in addition to many other diseases in which the inflammatory process enhances the disease activity.
Current efforts are focused on assessing how important the role of cytokines is in chronic malicious conditions, and a direct anticytokine therapy
is under development now.
However, none of our patients were treated with anticytokine therapy
, such as cytokine receptor antibodies, cytokine signaling inhibitors, TNF-[alpha] blockers, or thalidomide.
It is striking that most successful anticytokine therapy
has targeted the Th17 inflammatory axis.
in the patients with inflammatory intestinal diseases.
Next comes reviews of cytokines and their role in tumor stoma or metastasis, and the final papers cover discoveries in how cytokines can actually figure in treatment, including in combination cytokines therapy, vaccines, anticytokine therapy
, and in supportive care.