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(ant″i-kō-ag″yŭ-lā′shŏn) [ anti- + coagulation]
The prevention or hindering of the coagulation of blood, esp. by an anticoagulant drug. anticoagulate (-kō-ag′yŭ-lāt″)

prophylactic anticoagulation

The administration of anticoagulant drugs to patients who have a high risk for venous thromboembolism, e.g., patients admitted to medical wards of hospitals or undergoing certain forms of surgery, esp. on the hips or knees.


The practice reduces the likelihood of the formation of blood clots but increases the risk of bleeding.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
The criteria for thrombolytic and standard anticoagulation therapy modalities were defined as massive PE presenting with sustained hypotension (systolic blood pressure (SBP) <90 mm Hg for at least 15 min or requiring inotropic support, not due to a cause other than PE), pulselessness, or persistent profound bradycardia.
Given the desire to limit anticoagulation in the setting of an epidural collection, the procedure was completed with a heparinization duration of 1 hour 10 minutes.
In present study underuse of anticoagulation therapy was found in patients, only 10 (15.8%) patients were currently on anticoagulation therapy, out of which 5 (50.0%) were at high risk of developing cerebrovascular events with CHA2DS2VASc score of > 2.
"In patients for whom their providers were alerted, 35% elected to open the stroke-prevention order set, a very tiny percentage elected to read the AF guidelines, and about 64% exited but provided a rationale for omitting anticoagulation," Dr.
In conclusion, we suggest that the optimal management of symptomatic ACD causing DVT in old woman should include cyst excision and interposition of PA with saphenous vein graft accompanied by long-term anticoagulation for DVT.
Only 53.1% of patients with acute SVT received anticoagulation, and within this group, 10 patients had major bleeding.
"The current study demonstrated that S-LAAO [surgical left atrial appendage occlusion] was associated with a significantly lower rate of thromboembolism among patients without oral anticoagulation. In the cohort of patients discharged with oral anticoagulation, S-LAAO was not associated with [reduced] thromboembolism but was associated with a lower risk for hemorrhagic stroke presumably related to eventual discontinuation of oral anticoagulation among S-LAAO patients," reported Daniel Friedman, MD, and his coinvestigators.
Anticoagulation therapy with warfarin was continued as per current guidelines since we have no data on anticoagulation management in CALAA.
Maintaining stable anticoagulation is important because under-treatment increases the risk of thrombotic events, whereas over-treatment increases the risk of hemorrhage.
Anticoagulation is routinely required during hemodialysis to prevent clotting within the extracorporeal circuit (ECC).

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