avidin

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av·i·din

(av'i-din),
A glycoprotein, obtained from egg whites, that possesses a high affinity for biotin. Labeled avidin is allowed to bind to biotin-tagged antibodies to amplify antigen-antibody reactions that may be difficult to visualize. Ingestion of avidin can cause a biotin deficiency.
Synonym(s): antibiotin
[L. avidus, eager fr. aveo, to crave + -in]

avidin

(ăv′ĭ-dĭn)
n.
A protein found in uncooked egg white that binds to and inactivates biotin.

avidin

A 68-kD tetrameric glycoprotein found in egg white which has a high affinity for biotin, an association used in immunology for the avidin-biotinylated immunoperoxidase method. When eggs are eaten in excess, avidin-biotin avidity may cause biotin deficiency.

av·i·din

(av'i-din)
Glycoprotein obtained from egg whites that possesses a high affinity for biotin; ingestion can cause biotin deficiency.
[L. avidus, eager fr. aveo, to crave + -in]
References in periodicals archive ?
The 5' end of an oligonucleotide primer is attached to an antibiotin antibody (23).
In brief, PBMCs were labeled with a mixture of biotin-conjugated antibodies and antibiotin microbeads, and CD4+ cells were then obtained by negative selection.
After the sandwich immune complex formed, the microspheres were washed once in 200 [micro]L of PBS containing 0.5 mL/L Tween 20 on a 96-well vacuum filter plate, resuspended in the antibiotin RCA primer conjugate preannealed to circle, and then incubated for 30 min at room temperature.
Briefly, lymphocytes were allowed to react with CD4+ T cell biotin-antibody cocktail (biotin-conjugated monoclonal antibodies against CD8a, CD11b, CD11c, CD19, CD45R (B220), CD49b (DX5), CD105, anti-MHC class II, Ter-119, and TCR[gamma]/[delta]) and then incubated with antibiotin microbeads, followed by magnetic separation.
IFN-[gamma] spots were detected with phi-labeled goat antibiotin Ab (U-Cytech Biosciences) and a reagent that activates phi (reagent I + II, U-Cytech Biosciences).
The CliniMACS TCR [alpha]/[beta] System uses [alpha][beta] TCR-specific, biotin-labelled monoclonal antibodies combined with CliniMACS antibiotin reagent for highly selective depletion.

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