ECMO in this condition provided significant haemodynamic support and it ensured the weaning of the
antiarrhythmic and catecholamine drugs, thereby achieving rate control and sinus rhythm.
Prospective randomized comparison of
antiarrhythmic therapy versus first-line radiofrequency ablation in patients with atrial flutter.
BARCELONA--Catheter ablation of symptomatic atrial fibrillation produced significantly better quality of life after 12 months than did continued treatment with
antiarrhythmic drugs in a randomized, multicenter trial with 155 patients who had a history of failed drug treatment.
In accordance with the 2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death, implantable cardioverter defibrillator (ICD) implantation was performed (Figure 4), allowing adequate doses of
antiarrhythmic drugs.
Natural Drug Agents with Reported
Antiarrhythmic Properties.
"It's notable that
antiarrhythmic drug development has almost been stopped because the drugs don't work, with the possible exception of amiodarone, which requires an individualized risk/benefit assessment," according to Dr.
In contrast, despite a great unmet need for safer
antiarrhythmic drugs, developments in this field are expected to be much slower.
DISCUSSION: Amiodarone is an iodine containing highly lipophilic class III
antiarrhythmic drug used in ventricular and supraventricular arrhythmias.
The risk of proarrhythmia is present with
antiarrhythmic agents, and clinicians are cautioned to assess risk versus benefit before starting any of the agents.
(1986) reported that the effects of an ethanol extract of the plant Sophora flavescens Ait possessed
antiarrhythmic activity.
"In this study, a structured weight management program for highly symptomatic patients with atrial fibrillation reduced symptom burden and severity and reduced
antiarrhythmic use when compared with attempts to optimally manage risk factors alone," the authors wrote.
Drugs, including
antiarrhythmic drugs that prolong repolarization, do not uniformly prolong repolarization in all three layers of myocardium and Purkinje fibers, resulting in heterogeneity of repolarization.
