Hypertrophic cardiomyopathy is a new clinical ground where ranolazine has shown promising results in terms of its antianginal
Lopaschuk, "The antianginal
drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase," Circulation Research, vol.
Previous clinic studies have demonstrated that CDDP is safe and effective in the treatment of CHD; its antianginal
effect is even more effective than isosorbide dinitrate .
miltiorrhiza may be useful as an antianginal
drug because it has been shown to dilate coronary arteries in all concentrations, similar to P.
Assessment of antianginal
and antiischemic effect of trimetazidine and its effects on myocardial perfusion in patients with ischemic heart disease and stable angina.
A post hoc analysis from that trial suggested that ranolazine, a late sodium current inhibitor, also had potential as a glucose-lowering agent-something not seen with other antianginal
drugs, said Dr.
Any patient having compromised cardio-pulmonary or renal status or on any medications like beta blocker, antihypertensive, antianginal
drugs, anxiolytics or analgesics, obese patient (wt more than 80 kg), or patient hypersensitive to any drug used in the study, were excluded from the study.
(42) And in a six-month study of patients with known ischemic heart disease (poor blood circulation to heart muscle), magnesium supplementation led to an impressive decrease in angina attacks and a decrease in the use of antianginal
drugs such as nitroglycerin.
The bulletin said Reyes was given antianginal
drugs to stabilize oxygen delivery to her heart, but it gave her "no relief."
Electrophysiological effects of ranolazine, a novel antianginal
agent with antiarrhythmic properties.
The anti-ischemic and antianginal
properties of statins.
For example, in cardiovascular diseases, as frequencies of occurrence of myocardial infarction and cardiac arrest are more common from morning to noon, optimal antihypertensive and/or antianginal
drug is to be delivered in morning time .