anti-mullerian hormone

mül·le·ri·an in·hib·it·ing sub·stance (MIS),

a 535-amino acid glycoprotein secreted by the Sertoli cells of the testis. It is related to inhibin.
Farlex Partner Medical Dictionary © Farlex 2012


A gene on chromosome 19p13.3 that encodes anti-Müllerian hormone, a member of the transforming growth factor-beta gene family, which mediates male sexual differentiation. AMH causes regression of Müllerian ducts, which would otherwise differentiate into the uterus and fallopian tubes.
Molecular pathology
AMH mutations result in persistent Müllerian duct syndrome.

müllerian inhibiting substance

A 59 kD glycosylated preproprotein of the TGF-beta family encoded by AMH on chromosome 19p13.3 and produced by Sertoli cells in the prepubertal testes, which promotes müllerian duct involution during normal male sexual differentiation. The lack of MIS results in persistent müllerian duct syndrome.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Anti-mullerian hormone: above and beyond conventional ovarian reserve markers.
With the evolvement of anti-mullerian hormone (AMH) test, the value of the European market is increasing.
(8) demonstrated the role of patient's BMI, testosterone, anti-mullerian hormone and ovarian volume in predicting response to clomiphene citrate treatment.
The hormone, in this case, anti-Mullerian hormone or AMH, is secreted by cells in the ovary and is now widely recognised as a reliable circulating marker of ovarian reserve.
Anti-mullerian hormone (AMH) level tests the function of sertoli cells and can also be used instead of hCG test.
She wanted to do a blood test called an anti-Mullerian hormone (or AMH) test that would approximate the number of viable eggs she had.
Serum anti-Mullerian hormone (AMH) levels were determined by ELISA; assay sensitivity was 0.5 pmol/L and assay limit of quantification 1.2 pmol/L serum T was determined by a DPC Immulite[R] Assay System (Diagnostic Products, Los Angeles, CA); assay sensitivity was 0.17 nmol/L; interassay coefficient of variation ranged from 7.4 to 13%.
Interestingly, recent research conducted in mice suggests that PCOS might be related to a hormonal imbalance present in the mother before birth, in that pregnant women with PCOS have 30-percent higher levels of anti-Mullerian hormone than normal.
The PicoAMH Elisa diagnostic test measures circulating levels of anti-Mullerian hormone (AMH), a granulosa cell product in ovaries that is present only until menopause.
Anti-Mullerian hormone has been validated consistently only for predicting ovarian response during IVF
Age, antral follicle count (AFC), and anti-Mullerian hormone (AMH) levels are among the most important predictors of poor response to COS.
Ansh Labs' PicoAMH Elisa test measures the amount of Anti-Mullerian Hormone (AMH) in the blood.

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