anti-mitochondrial antibody


Also found in: Acronyms, Wikipedia.

anti-mitochondrial antibody

Any antibody that reacts to various mitochondrial antigens; one such antigen is M2, which evokes the production of an AMA present in 90-95% of Pts with PBC, some of whom also have scleroderma; AMA is directed against the ATPase lipoprotein present on the inner mitochondrial membrane
References in periodicals archive ?
While anti-nuclear antibody levels were negative, the anti-mitochondrial antibody level was elevated at 26.
PBC is most likely an autoimmune disorder (2), and anti-mitochondrial antibody (anti-M2) has been a diagnostically very useful marker: several studies have reported a positivity rate for anti-M2 of >95% in biopsy-confirmed PBC patients (3).
NASDAQ:HMGN) today announced it has obtained Food and Drug Administration (FDA) clearance to market the VIRGO Anti-mitochondrial Antibody (AMA) kit to screen patients for primary biliary cirrhosis, a disfunction of the liver.

Full browser ?