Anti-double-stranded DNA antibody | definition of anti-double-stranded DNA antibody by Medical dictionary
anti-double-stranded DNA antibody
anti-double-stranded DNA antibody An autoantibody against DNA, which is often present in systemic lupus erythematosus (SLE), measured in patients known to have antinuclear antibodies associated with lupus (glomerulo) nephritis, a major complication of SLE. Anti-ds DNA antibody testing is more specific than subjective interpretation of fluorescent staining patterns.
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References in periodicals archive
His antinuclear antibodies were positive, with a titre of 320, but anti-double-stranded DNA antibody
In addition, active SLE, especially if accompanied by anti-double-stranded DNA antibody
or low complement levels, predicts extreme prematurity.
Measurement of increases in anti-double-stranded DNA antibody
levels as a predictor of disease exacerbation in systemic lupus erythematosus: a long-term, prospective study.