anti-Xa assay


Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia.

anti-Xa assay

A test that monitors blood clotting in patients taking anticoagulant drugs, such as low molecular weight heparin or unfractionated heparin. Heparins bind to antithrombin, which inhibits clotting factor Xa. The degree to which factor Xa is inhibited is measured by this assay.
See also: assay
Mentioned in ?
References in periodicals archive ?
Generally, anti-Xa assays are readily available and widely used and can be relatively easily calibrated to accurately measure factor Xa inhibitor concentrations.
The correlations between clotting time values and actual heparin concentrations as determined by the anti-Xa assay were poor for each of the tests evaluated.
However, a significant positive bias was observed with the anti-Xa assay compared with the other methods.
Unfractionated heparin (UF) is commonly used in anticoagulant therapy and is monitored by a variety of methods including activated partial thromboplastin time (aPTT), anti-Xa assays, and during surgery or other invasive procedures by the activated clotting time (ACT).