anti-LKM

anti-LKM

An antibody against liver and kidney cells, sometimes found circulating in the blood of people with autoimmune hepatitis.
References in periodicals archive ?
Anti-LKM AMA-M2 (Euroline Liver Profile Euroimmun) Anti-Tg and Anti-TPO (Euroassay AntiTg+TPO IgG Euroimmun) tests were performed using the dot blot method at the Serology-Immunology unit.
Also 2 patients had ASMA one patient had anti-SS-A one patient had AMA and one patient had anti-LKM positivity (all were also ANA positive).
An extensive diagnostic workup discarded any other known etiology for liver disease, included viral serology for hepatitis (HAV, HBV, HCV, CMV, EBV, HSV, HIV), auto-antibodies (ANA, AMA, ASMA, anti-LKM, anti-Sp100, anti-gp210, anti-LC1, anti-SLA) and extensive toxicology screening.
Even though anti-LKM and anti-LM are the most developed autoantibodies in autoimmune DILI (Watkins and Seeff 2006), the transient appearance of c-ANCA in our patient could be attributed to the induction of immune mechanisms by QpE.