anti-IgE antibody

anti-IgE antibody

Allergy medicine An antibody directed against IgE. See Allergy.
References in periodicals archive ?
Down-regulation of Fc(epsilon)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody.
Downregulation of Fc(epsilon) RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody.
ORLANDO--Omalizumab, a monoclonal anti-IgE antibody, may be a good option for patients with treatment-refractory bullous pemphigoid (BP).
Studies using anti-IgE antibody in food allergy management are limited, but show promising results.
Currently available treatment using omalizumab (an anti-IgE antibody sold under the trade name Xolair) can block new interactions between IgE and FcR, but it is not designed to pry the molecules apart once they've formed a bond on the surface of a mast cell.
These results suggest that, after incubation with CAF, the anti-IgE antibody used in ELISA was unable to detect the IgE.
18) Omalizumab is a humanised monocolonal anti-IgE antibody that works by binding free IgE and thus preventing the interaction between free IgE and both the high and low affinity IgE receptors on inflammatory cells, such as basophils and mast cells.
It has been established that anti-IgE antibody induces passive cutaneous anaphylaxis (PCA) as a typical in vivo model for immediate hypersensitivity in anaphylactic reactions.
2003;167:1232-8), and the humanized monoclonal anti-IgE antibody omalizumab (Int.
A recombinant humanized monoclonal anti-IgE antibody, Xolair (omalizumab) can exert beneficial effects with a once- or twice-per-month administration.
New therapies that still may prove to have some utility include the anti-IgE antibody, omalizumab (Xolair); the anti-tumor necrosis factor agent, etanercept (Enbrel); and an experimental approach of using ultrasound waves to kill smooth muscle tissue in the bronchioles.