anti-Hu antibody


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Related to anti-Hu antibody: Hu antigen

anti-Hu antibody

any of the polyclonal immunoglobulin G autoantibodies directed against the proteins of the Hu antigen family; they are associated with paraneoplastic sensory neuronopathy and encephalomyelitis in oat cell carcinoma of the lung and more rarely, sarcoma and neuroblastoma. Also called type 1 antineuronal antibody.

anti-Hu antibody

An autoantibody associated with paraneoplastic encephalomyelitis. It is also known as ANNA-1 (antineuronal nuclear antibody-1).
See also: antibody