anthralin


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anthralin

 [an´thrah-lin]
an anthraquinone used topically in treatment of psoriasis.

anthralin

(an′thră-lĭn) [ anthr(acene) + -al + -in]
A synthetic hydrocarbon refined from anthracine. It is used in ointment form for treating various skin diseases (e.g., fungal infections and eczema).
References in periodicals archive ?
In a retrospective study of 37 pediatric patients in the Cleveland Clinic AA database, they found that almost two-thirds experienced at least 50% regrowth of hair with topical anthralin treatment.
Because of a high likelihood of no exposure potential, it was designated as "low priority." Anthralin is a topical medication approved for treating psoriasis; it is sequestered in the mitochondria of keratinocytes, where it triggers apoptosis and promotes the growth of new skin tissue (Sehgal et al.
Treatments can be topical--creams and ointments such as corticosteroids, vitamin D analogues, anthralin, retinoids, calcineurin inhibitors, salicyclic acid, coal tar (the oldest treatment for psoriasis) and moisturizers which can help alleviate skin dryness.
We have treated 24.5%of patients with topical corticosteroid lotion,--30.9%--with anthralin,--0.9%--with 2% minoxidil lotion,-- 0.9%--with calcipotriol lotion, 1.8% with topical calcineurin inhibitors, and 10% of cases with intralesional corticosteroids.
UVB light therapy, sunlight, oral and topical vitamin A derivatives, coal tar, salicylic acid, hydroxyurea (which can be combined with light therapy), anthralin and topical vitamin D derivatives often help.
As concerns the combination of CsA and topical drugs, which can be safely used to augment and accelerate the responsiveness to CsA, especially in regimens with low-dose CsA or while CsA dosage is tapering off, evidence exists for anthralin and calcipotriol alone or calcipotriol associated with betamethasone dipropionate as two-compound product (CBD).
Topical treatments Topical steroids Intralesional steroid injections Topical contact sensitizers Anthralin Minoxidil Topical retinoids Tacrolimus Systemic treatments Systemic corticosteroids Sulfasalazine Azathioprine Methotrexate Oral zinc sulphate Photo-and photochemotherapy PUVA NBUVB Excimer laser Miscellaneous and Non-pharmacological treatment Dermatography, wigs Hypnotherapy etc Topical treatment options
Topical anthralin therapy for refractory nail psoriasis.
Regarding topical therapies, tazarotene, anthralin, calcipotriol, and coal tar should be avoided as well, said Dr.
Early treatment of psoriasis included the use of various traditional agents such as arsenic, ammoniated mercury, crude coal tar, anthralin, corticosteroids etc.
Psoriasis Immune system Patches of Phototherapy, triggers an raised, reddish topical medications increased growth skin covered by including cycle of skin silvery-white Drithocreme cells, leading scales that form (anthralin), to overgrowth of on the elbows, Dovonex cells and knees, lower (calcipotriene), lesions.