In a retrospective study of 37 pediatric patients in the Cleveland Clinic AA database, they found that almost two-thirds experienced at least 50% regrowth of hair with topical anthralin
Because of a high likelihood of no exposure potential, it was designated as "low priority." Anthralin
is a topical medication approved for treating psoriasis; it is sequestered in the mitochondria of keratinocytes, where it triggers apoptosis and promotes the growth of new skin tissue (Sehgal et al.
Treatments can be topical--creams and ointments such as corticosteroids, vitamin D analogues, anthralin
, retinoids, calcineurin inhibitors, salicyclic acid, coal tar (the oldest treatment for psoriasis) and moisturizers which can help alleviate skin dryness.
We have treated 24.5%of patients with topical corticosteroid lotion,--30.9%--with anthralin
,--0.9%--with 2% minoxidil lotion,-- 0.9%--with calcipotriol lotion, 1.8% with topical calcineurin inhibitors, and 10% of cases with intralesional corticosteroids.
UVB light therapy, sunlight, oral and topical vitamin A derivatives, coal tar, salicylic acid, hydroxyurea (which can be combined with light therapy), anthralin
and topical vitamin D derivatives often help.
As concerns the combination of CsA and topical drugs, which can be safely used to augment and accelerate the responsiveness to CsA, especially in regimens with low-dose CsA or while CsA dosage is tapering off, evidence exists for anthralin
and calcipotriol alone or calcipotriol associated with betamethasone dipropionate as two-compound product (CBD).
Topical treatments Topical steroids Intralesional steroid injections Topical contact sensitizers Anthralin
Minoxidil Topical retinoids Tacrolimus Systemic treatments Systemic corticosteroids Sulfasalazine Azathioprine Methotrexate Oral zinc sulphate Photo-and photochemotherapy PUVA NBUVB Excimer laser Miscellaneous and Non-pharmacological treatment Dermatography, wigs Hypnotherapy etc Topical treatment options
* Broadband UVB (BB-UVB) was first used during the 1950s, with crude tar or anthralin
, but is rarely used today.
therapy for refractory nail psoriasis.
Regarding topical therapies, tazarotene, anthralin
, calcipotriol, and coal tar should be avoided as well, said Dr.
Early treatment of psoriasis included the use of various traditional agents such as arsenic, ammoniated mercury, crude coal tar, anthralin
, corticosteroids etc.
Psoriasis Immune system Patches of Phototherapy, triggers an raised, reddish topical medications increased growth skin covered by including cycle of skin silvery-white Drithocreme cells, leading scales that form (anthralin
), to overgrowth of on the elbows, Dovonex cells and knees, lower (calcipotriene), lesions.