At time of permanent section, the single most valuable stain is the reticulin stain to distinguish the preserved pattern in normal anterior pituitary gland
from the disrupted pattern in pituitary adenoma; unfortunately, reticulin stains at the time of intraoperative consultation are usually unavailable and/or impractical.
Higuchi et al., "Expression of chemokine CXCL10 in dendritic-cell-like S100[beta]-positive cells in rat anterior pituitary gland
," Cell and Tissue Research, vol.
As with men, women's reproduction is controlled by hormonal activity, from the hypothalamus, the anterior pituitary gland
and the ovaries (Palmer 1999).
Unlike the anterior pituitary gland
, this lobe does not produce hormones.
Diagnostic tests of the endocrine system focus on hormone levels; the interrelationships among the hypothalamus, the anterior pituitary gland
, and other endocrine glands; or the substrates controlled by the hormone.
When the anterior pituitary gland
is involved, the production of growth hormone may drop.
GH is secreted by the anterior pituitary gland
. Its release is stimulated by growth-hormone-releasing hormone (GHRH), which is secreted by the hypothalamus.
When stimulated by thyroid stimulating hormone/TSH from the anterior pituitary gland
in response to decreased circulating thyroid hormone leading to decreased negative feedback and TSH release, the thyroid gland releases about 90% T4 (pre-hormone), about 9% T3 (the active, stimulating form of thyroid hormone), about 1% RT3 (an inhibitory version of thyroid hormone), and a smidgen of T2.
Thus it affects the development of keratinocytes and cause aberrations in the hair, sebaceous glands, ecrine and apocrine glands, nails, teeth, lenses and conjunctiva of the eyes, anterior pituitary gland
, nipples and the ears (4).
Adrenocorticotropic hormone (ACTH): Also known as corticotropin, is a hormone produced and secreted by the anterior pituitary gland
. It is an important component of the hypothalamic-pituitary-adrenal (HPA) axis and often is produced in response to biological stress (along with corticotropin-releasing factor from the hypothalamus).
The superior hypophysial artery enters at the interface between the ventral hypothalamus and infundibulum and supplies the anterior pituitary gland
. The inferior hypophysial artery enters the ventral region of the posterior pituitary gland.
We froze the anterior pituitary gland
at -80[degrees]C for PRL and LH assays.