keratoglobus(redirected from anterior megalophthalmos)
a developmental anomaly of the cornea, which is of abnormal size at birth and continues to grow, sometimes reaching a diameter of 14 or 15 mm in the adult.
Congenital anomaly consisting of an enlarged anterior segment of the eye.
[kerato- + L. globus, ball]
megalocorneaAn X-linked recessive, nonprogressive enlargement of the cornea to 13 mm or greater, which is present at birth; 90% of cases occur in males. The cornea and the limbus are enlarged but histologically normal. Associated findings include anterior megalophthalmos, enlarged ciliary ring with zonular stretching (leading to phacodonesis), ectopia lentis, iridodonesis, iris stromal hypoplasia, posterior embryotoxon, transillumination defects, Krukenberg spindles, trabecular meshwork pigmentation, posterior embryotoxon, Rieger anomaly, goniodysgenesis and cataracts. It is usually isolated, but may be associated with other ocular and systemic findings.
keratoglobusA condition in which the cornea bulges abnormally causing MYOPIA and distorted vision.
A rare, usually bilateral, protrusion of the cornea with general thinning, especially in the periphery. The condition is usually present at birth and generally does not progress. Some cases may be acquired perhaps as the end-stage of keratoconus. The diameter of the cornea is normal or slightly increased and the intraocular pressure is normal as the condition is not associated with congenital glaucoma. Complications include perforation after minor trauma and corneal hydrops. It is sometimes associated with Leber's congenital amaurosis, Ehlers-Danlos syndrome and blue sclera. Syn. macrocornea. See megalocornea.