Nasdaq: IDRA) today announced the publication of studies on the chemistry of novel compounds that have been shown to act as antagonists
for Toll-like Receptors (TLR) 7 and 9.
First generation cannabinoid type 1 (CB1) receptor antagonists
are directed against CB1 receptors in the brain and in peripheral tissues such as adipocytes.
PHILADELPHIA -- Research shows that proprietary non-brain penetrant cannabinoid subtype 1 (CB1) receptor antagonists
developed by Jenrin Discovery are able to produce metabolically favorable effects in peripheral tissues, including fat and liver.
We continue to advance evaluation of our drug candidates targeted to TLRs, and among our current presentations will be data on the mechanism of action of our TLR antagonists
and results from the evaluation of antagonists
in preclinical models of colitis and of treatment of collagen-induced arthritis," said Dr.
The corporate R&D portfolios (more than one project) for TLR Agonists, Antagonists
, Adjuvants and TLR-Adjuvanted Vaccines is contained in this Competitor Analysis.
The report includes a compilation of current active projects in research and development of Muscarinic Receptor Agonists & Antagonists
for the treatment of cognitive impairment, overactive bladder or urinary incontinence and chronic obstructive pulmonary disease (COPD).
Nasdaq: IDRA) today announced that presentations from studies evaluating its novel Toll-like Receptor (TLR) antagonist
candidates in preclinical models of lung inflammation and psoriasis were made at the Federation of Clinical Immunology Societies (FOCIS) 2008 Annual Meeting held in Boston, MA, June 5-9.
Several studies have reported conflicting results regarding the outcome of COS-IUI cycles using GnRH antagonists
in terms of clinical pregnancy rate.
Since NK1 receptor antagonists
are used in combination with 5-HT3 receptor antagonists
, CINVANTI offers a strong strategic and operational fit with Heron's existing commercial product, SUSTOL[R], our extended-release, injectable product that incorporates the 5-HT3 receptor antagonist
granisetron and is also indicated for the prevention of CINV.
LISBON -- Women undergoing assisted reproduction had similar pregnancy rates with gonado-tropin-releasing hormone agonist and antagonist
protocols, but less ovarian hyperstimulation syndrome with the GnRH-antagonist
protocol in a large randomized trial.
Gonadotrophin-releasing hormone antagonists
for assisted conception: a Cochrane review.
M2 EQUITYBITES-November 10, 2014-Heron Therapeutics reveals development program for a P/neurokinin-1 receptor antagonist