antagonist

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Related to antagonistically: conferred, exultation, underwent, waylaid

antagonist

 [an-tag´o-nist]
antagonistic muscle. (see illustration.)
1. a substance that tends to nullify the action of another, as a drug that binds to a cellular receptor for a hormone, neurotransmitter, or another drug blocking the action of that substance without producing any physiologic effect itself. See also blocking agent.
2. a tooth in one jaw that articulates with one in the other jaw.
α-adrenergic antagonist alpha-adrenergic blocking agent.
β-adrenergic antagonist beta-adrenergic blocking agent.
folic acid antagonist see folic acid antagonist.
H1 receptor antagonist any of a large number of agents that block the action of histamine by competitive binding to the H1 receptor. Such agents also have sedative, anticholinergic, and antiemetic effects, the exact effect varying from drug to drug, and are used for the relief of allergic symptoms and as antiemetics, antivertigo agents, sedatives, and antidyskinetics in parkinsonism. This group is traditionally called the antihistamines.
H2 receptor antagonist an agent that blocks the action of histamine by competitive binding to the H2 receptor; used to inhibit gastric secretion in the treatment of peptic ulcer.

an·tag·o·nist

(an-tag'ŏ-nist),
Something opposing or resisting the action of another; certain structures, agents, diseases, or physiologic processes that tend to neutralize or impede the action or effect of others. Compare: synergist.

antagonist

(ăn-tăg′ə-nĭst)
n.
1. Physiology A muscle that counteracts the action of another muscle, the agonist.
2. A drug or chemical substance that interferes with the physiological action of another, especially by combining with and blocking its receptor.

an·tag′o·nis′tic adj.
an·tag′o·nis′ti·cal·ly adv.

antagonist

Anatomy
A muscle that opposes the movement of agonist muscles and returns a limb to its initial position.

Pharmacology
A substance that partially or completely nullifies the effect of another agent; a chemical entity that is not naturally found in the body which occupies a receptor, produces no physiologic effects and prevents endogenous and exogenous chemicals from producing an effect on that receptor.

an·tag·o·nist

(an-tag'ŏ-nist)
Something opposing or resisting the action of another; any structure, agent, disease, or physiologic process that tends to neutralize or impede some action or effect.
Compare: synergist

antagonist

1. A muscle that acts to oppose the action of another muscle (the agonist).
2. A drug that counteracts or neutralizes the action of another drug. The antonym of antagonist is agonist.

Antagonist

A substance that tends to nullify the action of another.
Mentioned in: Withdrawal Syndromes

antagonist 

1. An antagonistic muscle.
2. A substance (e.g. a drug, hormone or neurotransmitter) that depresses the action of an agonist or binds to a cell receptor without eliciting a physiological response (e.g. excitation or inhibition). Examples: atropine and hyoscine which block the effect of acetylcholine acting on cholinergic receptors and timolol which blocks adrenergic receptors. See agonist.

an·tag·o·nist

(an-tag'ŏ-nist)
Something opposing or resisting the action of another; certain structures, agents, diseases, or physiologic processes that tend to neutralize or impede the action or effect of others.
Compare: synergist
References in periodicals archive ?
To examine the extent of transcriptional remodeling for Dex- and Gen-regulated genes, co-regulated genes from the overlapping gene lists were classified as a) induced by both Dex and Gen, b) repressed by both Dex and Gen, c) anti-correlated (genes with opposing direction of regulation), or d) antagonistically regulated (Figure 2D); a representative gene demonstrating each of these patterns is provided in Figure 2E.
Ishaq Dar it could be granted that he is taking such coercive measurements to restrain Pakistan's economy from all kind of external aggression; i.e "India could not be further titled as favorite nation" antagonistically said and also quarrelsome mode while talking about Indian smuggling and hoarding.
PICKLE and CLF antagonistically determine root meristem activity since loss of PICKLE function causes a decrease in meristematic activity while loss of CLF function causes increased meristematic activity (Aichinger et al., 2011).
Fgf-8 has been proposed to work antagonistically with Bmp-4 to specify the sites of tooth initiation.It is also shown that mesenchymal Bmp-2 & epithelial Bmp-4 antagonise the induction of mesenchymal Pax -9 by Fgf-8.(Figure 1)
As Dan Brayton reviews the term, ecophobia is a "cultural tendency to relate antagonistically to nature" (226).
She also reconciles herself with her infant son, whom she initially perceives so antagonistically in 'At the Bay' (1921).
Although the biosensor responded antagonistically towards the combination of toxicants, the results showed that the qualitative detection for the mixture of toxicants is possible.
Vertebral flexors work antagonistically with those that extend the vertebral column and they are responsible for stabilizing the vertebral column, maintaining the optimum level for co-contraction and an efficient metabolic rate in these muscles (Stokes et al.
It will however be important for mining companies and government officials to work together less antagonistically and for the mining industry to change its generally negative perception.
The active critics of Israel in our online sample show (as expected) no pro-Israeli pattern and position themselves quite antagonistically in favor of the Palestinians, but they display no antisemitic pattern.
Antagonistically, Israel has continuously supported the Kurdish community in Turkey and Northern Iraq providing military training, as well as funding economic development.
He furthermore, reiterated, "Of course Portugal's stands at that time were positive, but many European countries have encountered the Iranian nation antagonistically, without having any logical reason for doing so."