antagonist drug

antagonist drug 

A drug that blocks or reduces the effect of a neurotransmitter. See beta-blocker.
References in periodicals archive ?
This patent broadens previously issued patent by expanding the use of Onvansertib to encompass combination therapies with any anti-androgen and androgen antagonist drug for the treatment of metastatic and non-metastatic castrate-resistant prostate cancer.
The antagonist drug the team gave the mice during their periods of isolation effectively lessened the negative effects of the isolation.
(Protagonist) to develop, manufacture and commercialize PTG-200, a first-in-class, oral interleukin-23 receptor (IL-23R) antagonist drug candidate in development for the treatment of Crohns disease and ulcerative colitis (UC).
The study is designed to evaluate the potential of GMI-1271, GlycoMimetics' E-selectin antagonist drug candidate, in combination with chemotherapy, as a treatment for patients with both newly diagnosed and relapsed/refractory AML.
Several methodologies are currently available for measuring serum TNF antagonist drug concentrations and for detecting ADAs, which show significant variations in both analytical sensitivity and specificity (45-48).
If the former, studies would need to determine whether a person would benefit from treating OSA to reduce aldosterone levels; if the latter, whether a person would benefit from an aldosterone antagonist drug to reduce the severity of OSA.
The 5HT3 receptor antagonist drug granisetron, which is more potent and long acting than ondansetron against emesis associated with chemotherapy, have been found to be very effective for preventing PONV after laparoscopic cholecystectomy.
The various regimens use different combinations of periods of treatment with unfractionated heparin, low-molecular-weight heparin, or a vitamin K antagonist drug during the first trimester, during weeks 14-36, and during the last weeks of pregnancy.
The implant then delivers therapeutic levels of the antagonist drug, naltrexone, into the bloodstream which can curb one's cravings for alcohol or opioids.
Palosuran (ACT-058362), the only UT antagonist drug candidate, when administered intravenously, protected against renal ischemia in a rat model [4].
Next, they blocked the activity of CXCR4 in the MPNST mice using either genetic manipulation or an FDA-approved antagonist drug for CXCR4 called AMD3100.