ansamycins

ansamycins

Drugs used to treat TUBERCULOSIS. An example is rifabutin (Mycobutin).
References in periodicals archive ?
Antimycobacterial activities of two newer ansamycins, R-76-1 and DL 473.
Anti-leprosy activity of ofloxacin and ansamycins in mice.
In addition to rifalazil, ActivBiotics expects to have a full pipeline of long lasting, extremely potent ansamycins with broad spectrum coverage in clinical development during this timeframe.
In the 1970s, scientists isolated a family of natural antibiotics, called ansamycins, that microbes secrete--seemingly, to kill off competitors.
It is the researchers' hypothesis that prodrugs yielding hydroquinone ansamycins intracellularly may be effective Hsp90 inhibitors.
Geldanamycin, heat shock protein 90-binding benzoquinone ansamycin, inhibits steroid-dependent translocation of the glucocorticoid receptor from the cytoplasm to the nucleus.