(38) tried the CST in a case-control study, validated it using the Sniffin' Sticks orthonasal test, and ranked it as an easy and reliable test method that can be performed for discriminating normosmic, hyposmic, and
anosmic individuals in daily clinical practice.
"I think
anosmics are always waiting for the day their sense of smell will come back but I don't think mine ever will, as it's been 13 years."
Previous studies have demonstrated that olfactory training can at least partially restore olfactory function in
anosmic patients, especially in patients with smell loss after an upper respiratory tract infection [11, 12], but also in patients with Parkinson's disease [14].
A similar proportion of patients in the steroid group--2 of 18 (11.l%)--experienced a clinically relevant improvement at 4 months; 1 patient in the post-URTI category improved from hyposmic to normosmic, and 1 patient in the idiopathic category improved from
anosmic to hyposmic.
With the aim of making the social stress stimulus equal for all animals, social interaction involved contact with
anosmic intruder subjects.
A similar conclusion was supported by some work on
anosmic pigeons.
They can be hyperosmic (very sensitive), hyposmic (the baseline category) and
anosmic. Contact: Jane Friedrich, Department of Food Science and Technology, Cornell University, New York State Agricultural Experiment Station, Geneva, NY 14456.
In their study, some observers were made
anosmic by flushing zinc sulfate through the nasal pathway, and other observers received a sham-anosmia procedure.
Half of the mice were housed during 30 days and employed as experimental or control animals; the remainder were used as <<opponents>> and were temporally rendered
anosmic by zinc sulphate.
Symptom severity was rated as absent (0), intermittent (1), or constant (2), and sense of smell was rated as excellent (0), impaired (1), or
anosmic (2).
In a careful cross-comparison, Cometto-Muniz and Cain found that the localization procedure produced equivalent results among normosmic and
anosmic subjects, as well as results equivalent to forced-choice discrimination among the latter group (26).
In addition, patterning is first noticed, and most exaggerated, in the vicinity of the goal box (Ludvigson, 1969; Ludvigson & Sytsma, 1967; Seago, Ludvigson, & Remley, 1970), and
anosmic rats do not develop the patterned responding, but will do so if provided with a differential visual cue (Seago, Ludvigson, & Remley, 1970).
