anophthalmia

Also found in: Dictionary, Thesaurus, Financial, Encyclopedia, Wikipedia.

Related to anophthalmia: microphthalmia, the woman

anomaly

[ah-nom´ah-le]

marked deviation from normal. adj., adj anom´alous.

Axenfeld's anomaly a developmental anomaly characterized by a circular opacity of the posterior peripheral cornea, and caused by an irregularly thickened, axially displaced Schwalbe's ring.

congenital anomaly (developmental anomaly) absence, deformity, or excess of body parts as the result of faulty development of the embryo.

Ebstein's anomaly see ebstein's anomaly.

May-Hegglin anomaly a rare dominantly inherited disorder of blood cell morphology, characterized by RNA-containing cytoplasmic inclusions (similar to Döhle bodies) in granulocytes, by large, poorly granulated platelets, and by thrombocytopenia.

an·oph·thal·mi·a

(an'of-thal'mē-ă),

Congenital absence of all tissues of the eyes.

Synonym(s): anophthalmos

[G. an- priv. + ophthalmos, eye]

Farlex Partner Medical Dictionary © Farlex 2012

an·oph·thal·mi·a

(anof-thalmē-ă)

Congenital absence of all tissues of the eyes.

[G. an- priv. + ophthalmos, eye]

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

anophthalmia

Congenital absence of all tissues of the eyes. It is due to a failure of the outgrowth of the optic vesicle to form the optic cup. However, in many cases some development occurs and there is a rudimentary presence of one or both eyes, such as extreme microphthalmia. Syn. anophthalmos; anophthalmus; anopia. See optic cup; microphthalmia; monophthalmia; optic vesicle.

an·oph·thal·mi·a

, anophthalmos (anof-thalmē-ă, -mŏs)

Congenital absence of all tissues of the eyes.

[G. an- priv. + ophthalmos, eye]

Medical Dictionary for the Dental Professions © Farlex 2012

References in periodicals archive ?

FitzPatrick, "Anophthalmia and microphthalmia," Orphanet Journal of Rare Diseases, vol.

Management of Congenital Clinical Anophthalmos with Orbital Cyst: A Kinshasa Case Report

The frequency of strabismus was observed in 42 (27.6%) patients, cataract in 39 (25.6%) patients, extreme myopia in 32 (21.1%) patients 13 (8.5%) persons of microphthalmia, 8 (5.3%) individuals with anophthalmia, 9 (5.9%) patients of astigmatism and 6 (3.9%) patients of nystagmus, while keratoconus, glaucoma and retinitis pigmentosa were observed in single patient (0.7%)each.

MATERNAL CONSANGUINITY: THE MOST PROBABLE CAUSATIVE FACTOR OF GENETIC EYE DISORDERS

These include a single case of myelomeningocele and a single case of anophthalmia with severe oblique facial clefts and amniotic banding.

Efavirenz in pregnancy

Peter, 40, a painter and decorator, has dedicated the past seven years to researching the effects of fungicides on children born with anophthalmia (no eyes) or microphthalmia.

THEY KNEW CROP SPRAY COULD PUT BABIES AT RISK; Leaked letter could be vital in families' fight for compensation for children blinded after exposure to fungicide

([paragraph]) Structural eye abnormalities (microphthalmia/ anophthalmia, coloboma, cataract, intraocular calcifications, and chorioretinal anomalies [e.g., atrophy and scarring, gross pigmentary changes, excluding retinopathy of prematurity]); optic nerve atrophy, pallor, and other optic nerve abnormalities.

Population-Based Surveillance of Birth Defects Potentially Related to Zika Virus Infection--15 States and U.S. Territories, 2016

Specifically, the presence of one defective copy of PAX6 results in ocular malformations, but mutations in both copies of PAX6 cause ocular phenotypes that are more severe (e.g., anophthalmia) and brain abnormalities that are incompatible with life [6, 39, 40].

Phenotypic Variation in a Four-Generation Family with Aniridia Carrying a Novel PAX6 Mutation

Down syndrome 2 Talipes 2 11 10.58% Choanal atresia 1 equinovarus Multiple anomalies 4 Anophthalmia 1 Table 2.

Cross-sectional study of need of targeted USG and its benefits in decreasing foetal and maternal morbidity and mortality by obstetric decision making in a low resource setting

Bunyan et al., "SOX2 anophthalmia syndrome: 12 New cases demonstrating broader phenotype and high frequency of large gene deletions," British Journal of Ophthalmology, vol.

SOX5-Null Heterozygous Mutation in a Family with Adult-Onset Hyperkinesia and Behavioral Abnormalities

Morphological studies showed the abnormalities such as distorted axis, cryptophthalmia, anophthalmia, open eyelids, micromelia, phocomelia, agnathia, hydrocephaly, angular tail and subcutaneous hemorrhages.

Cadmium induced Teratogenic Effects in Developing Mus musculus

microphthalmia and anophthalmia and up to 20% have an identifiable

Congenital abnormalities of the optic nerve: this first article in a two-part series on optic nerve abnormalities concentrates on congenital conditions with a selection of case studies and short discussion

Anophthalmia and microphthalmia have been reported in rats exposed during organogenesis to verteporfin at 40 times the dose used in humans.

Pregnancy and the eye

The participant was "Yaffa," a 13-year-old girl with severe-profound intellectual disability, blindness due to bilateral congenital anophthalmia, and mild conductive hearing disorder.

Using background music to reduce problem behavior during assessment with an adolescent who is blind with multiple disabilities