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a term proposed to designate a single, localized anomaly occurring during morphogenesis, together with the pattern of subsequent morphologic defects that stem from it.
1. A malformation together with its subsequently derived structural changes.
2. Synonym(s): sequence
anomaladA dysmorphogenic complex characterised by a primary malformation and its derived structural defects; for example, Pierre-Robin syndrome with cleft palate, glossoptosis and micrognathia.
A malformation together with its subsequently derived structural changes.