In fact, there are several primary contributors in the emergence of androgen-independent metastatic prostate cancer such as activation of survival pathways, including apoptosis, suppression of anoikis
resistance, (13) and increased neovascularization.
Loss of expression of tropomyosin-1, a novel class II tumor suppressor that induces anoikis
, in primary breast tumors.
00 Bluecoat Story Night The Bluecoat, School Lane, 0151 702 5324, to Fri 18 Nov MUSIC Mogwai Camp and Furnace, 67 Greenland Street, 0151 708 2890, Mon 24 Oct Anoikis
: Howling Into the Sun Anoikis
is dancer and choreographer Melissa Pasut and electroacoustic composer/ filmmaker Andrew Leslie Hooker, who on this occasion is joined by collaborative artist Rachel Sweeney (dancer/ choreographer) Capstone Theatre, Shaw St, 0844 800 0410, Mon 24 Oct, PS10.
In a 2004 publication, Higuchi and Jass (11) updated these concepts, stating: "Using more modern terminology, the hyperplastic polyp can be defined as a lesion caused by the inhibition of programmed cell death or apoptosis," which they explain is probably a special form of apoptosis called anoikis
that is associated with programmed exfoliation of surface epithelial cells.
Furthermore, EUG induces alteration on cellular architecture probably by perturb cytoskeleton dynamics leading to a cytoplasmic retraction, shrinkage, pyknosis and cell detachment culminating in anoikis
, especially in MCF-7, SiHA and SK-MEL-28 cells.
The presence of CTM supports the speculation that cells within CTM have a survival advantage via protection from anoikis
Polyphenon E, a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis
and tumorigenic P[C.
It has been reported that SIRT1 increases cell invasion, anoikis
resistance, and EMT of GC cells .
Mechanisms that link the oncogenic epithelial-mesenchymal transition to suppression of anoikis
Ebola virus glycoprotein-mediated anoikis
of primary human cardiac microvascular endothelial cells.
DOC-2/hDab-2 inhibits ILK activity and induces anoikis
in breast cancer cells through an Akt-independent pathway.
Walden PD, Globina Y, Nieder A (2004) Induction of anoikis
by doxazosin in prostate cancer cells is associated with activation of caspase-3 and a reduction of focal adhesion kinase.