annotation

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annotation

Bioinformatics A term of art referring to analysis and commentary added to sequence data in databases, which provide contextual information about coding and non-coding sequence within genes, patterning and motifs, similarities, known or predicted protein structure and function, and links to external data (e.g., clinical observations).
Informatics A critical or explanatory note, usually included in a bibliographical entry or reference, to provide additional data.

annotation

process used in GENOMICS for analysis of NUCLEOTIDE SEQUENCES to identify the GENES (both PROTEIN-coding and protein non-coding, such as those for rRNA and tRNA), their regulatory sequences (see OPERON MODEL and their functions. Annotation also includes characterization of MOBILE GENETIC ELEMENTS and REPETITIVE DNA. See also BIOINFORMATICS.
References in periodicals archive ?
As an example, we load the GOLD ontology and then use OntoGloss to annotate two numbers 2004 and 10 in the Web page 1 and 2.
KIM is another general purpose annotation tool that uses KIM Ontology (KIMO) and a knowledge base of general important terms to automatically annotate a document.
Knowledge Station is a powerful research tool that allows users to view eBooks off line, download documents, and annotate text with highlights, notes, and bookmarks.
Leeson annotates his bibliography of reviews, providing a detailed and historical overview of the critical reception of plays by Hansberry as well as To Be Young, Gifted and Black and Raisin (the musical), adaptations produced by Robert Nemiroff and based on Hansberry's writings, and the filmed versions of A Raisin in the Sun.
A Bulgarian lawyer specializing in minority language rights, Avramov introduces in English, legal documents relating to Islam in Bulgaria, then quotes and annotates them in Bulgarian.