ANXA3

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ANXA3

A gene on chromosome 4q21.21 that encodes annexin 3, a calcium-dependent phospholipid-binding protein that plays a role in regulating cellular growth and signal transduction pathways. It inhibits phospholipase A2 and has anti-coagulant properties.

References in periodicals archive ?

The differential expression of annexin A3 (ANXA3) plays a major role in tumorigenesis, drug resistance, and metastasis [7].

Annexin A3 primary antibodies (ab127924) were obtained from Abcam.

Sun, "The role of annexin A3 playing in cancers," Clinical and Translational Oncology, vol.

Bang et al., "Expression and Prognostic Relevance of Annexin A3 in Prostate Cancer," European Urology, vol.

Li et al., "Quantitative proteome analysis reveals annexin A3 as a novel biomarker in lung adenocarcinoma," Journal of Pathology, vol.

Raimondo et al., "Primary cell cultures from human renal cortex and renal-cell carcinoma evidence a differential expression of two spliced isoforms of annexin A3," American Journal of Pathology, vol.

Pan, "Increased expression of annexin A3 is a mechanism of platinum resistance in ovarian cancer," Cancer Research, vol.

Song et al., "Annexin A3 is associated with a poor prognosis in breast cancer and participates in the modulation of apoptosis in vitro by affecting the Bcl-2/Bax balance," Experimental and Molecular Pathology, vol.

Lubman et al., "Annexin A3 is selectively expressed in MET-like as compared to EMT-like breast cancer stem cells," Cancer Research, vol.

Larkin et al., "Annexin A3 is a breast cancer marker secreted by neoplastic cell lines and involved in cell migration, anticancer research," Anticancer Research, vol.