Peripheral smear showed elliptocytes which were more than 50%, there was marked anisocytosis
, poikilocytosis and red cell fragmentation (fig-1a).
(5,7,8) An elevated red cell distribution width (RDW) means that there is anisocytosis
, or varying cell diameters in the RBC population.
Among the preoperative parameters associated with the red blood cells system, the erythrocyte count, hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin concentration, the rate of the average weight of corpuscular hemoglobin, and the coefficient of variation of volume distribution of erythrocytes (anisocytosis
) were analyzed in the study.
Her blood film demonstrated mild-moderate anisocytosis
and occasional target cells but no abnormal white cell or platelet morphology.
The peripheral blood smear showed pancytopenia with RBCs anisocytosis
, occasional schistocytes, and no blasts.
There was marked anisokaryosis and anisocytosis
. Binucleated and multinucleated cells as well as karyomegaly were multifocally observed.
Investigations revealed a hemoglobin =9.2g/dl, White cell count =5000/cmm (neutrophils=20%, lymphocytes=70%, monocytes=08%, eosinophils=02%), platelet count = 206,000/cmm, hematocrit =30.2, mean corpuscular volume =87.3fL, anisocytosis
, polychromasia and a reticulocyte count =2%.
On morphology, platelets are increased in counts, with platelet anisocytosis
A peripheral blood smear showed anisocytosis
, and target cell and reticulocyte was 3.5% (normal range: 1-1.5%).
Previously various morphological alterations such as hypochromia, polychromia, stomatocyte, anisocytosis
and poikilocytosis in experimentally infected rats and in naturally occurring cases of trypanosomiasis in camels have been reported (Abd El-Baky and Salem, 2011).
Evaluation of RDW-CV, RDW-SD, and MATH-1SD for the detection of erythrocyte anisocytosis
observed by optical microscopy.