Histopathology was characterized by sheets of round to ovoid cells with anisocytosis
, eccentrically placed nuclei with a prominent nucleoli.
Laboratory findings in iron deficiency Complete blood count: RDW>14 RBC: low Hb, Hct: low according to age and gender MCV: low according to age and gender When specifying the lower limit of MCV: 70+age (for >10 years) (if MCV is <72, generally abnormal) Upper limit of MCV: 84 + age x 0,6 (for >6 months) (if MCV>98: always abnormal) MCH<27 pg MCHC<30% Thrombocytosis Rarely: Thrombocytopenia, leukopenia Peripheral smear: Hypochromia Microcytosis Anisochromia Anisocytosis
Pencil cells Rarely: bazophilic stippling, target cells, hypersegmented neutrophils Serum ferritin<12 ng/mL (a) Serum iron: <30 mcg/dL (a) TIBC>480 mcg/dL Transferrin saturation (Iron/TBCx100)<16% Metzner index (MCV/RBC)<13 (a) May change by age, gender and other factors.
Augmented hemolysis usually lead to reduction in Hb, TEC and Hct and are escorted by elevated reticulocytes counts, amplified anisocytosis
, increased red cell dissemination width and volumes.
Erythrocyte morphology showed microcytosis, hypochromia, and anisocytosis
2008), increased rate of destruction or reduction in rate of formation of erythrocytes and altered cellular composition of blood leading to anemia, anisocytosis
, eosinophilia and leucopenia and also due to impaired absorption of folic acid (Hardman and Limbird, 1996) and disruption of liver biosynthesis of heme (Woods and Fowler, 1986).
Reactive mesothelial cells with hyperplasia can be seen in hydrocoele fluid, The cells show anisocytosis
and pleomorphism and have a moderate amount of pale cytoplasm.
A peripheral blood film revealed poikilocytosis, anisocytosis
, and nucleated red cells.
Microscopic examination of the blood smears showed nucleated RBCs, basophilic stippling and anisocytosis
at 1-7% parasitaemia.
9 Platelets * * * Mean Platelet Volume * * * Neutrophils 7 29 58 Bands 54 50 35 Lymphocytes 10 9 5 Monocytes 7 0 2 Metamyelocyte 12 9 0 Myelocyte 8 2 0 Promyelocyte 2 1 0 Nucleated Red Blood Cells 2 0 2 Polychromasia present [dagger] [dagger] Poikilocytosis present [dagger] present Anisocytosis
present [dagger] present Microcytes present [dagger] [dagger] Spherocytes present [dagger] [dagger] Mega-thrombocytes present present [dagger] Absolute Neutrophils 3.
+ to +++ 5 ++ 4 0 Microcytosis + 3 ++ 3 0 Hypochromia + 3 ++ 3 0 Reticulocytes (%) 0.
Peripheral smear revealed significant anisocytosis
, microcytosis, hypochromia and poikilocytosis.
1%) had normochromic features with anisocytosis
, 15 (5.