aniridia


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aniridia

 [an″ĭ-rid´e-ah]
congenital absence of the iris.

an·i·rid·i·a

(an'i-rid'ē-ă), [MIM*106210]
Absence of the iris. Compare: irideremia.
[G. an- priv. + irid- + -ia]

aniridia

/an·irid·ia/ (an″ĭ-rid´e-ah) congenital absence of the iris.

aniridia

[an′i·rid′ē·ə]
Etymology: Gk, a, without + iris
an absence of the iris, a usually bilateral, hereditary anomaly. Often, a rudimentary stump is visible through a gonioscope.

aniridia

Ophthalmology A congenital AD or AR condition characterized by a virtually complete absence of the iris, which may be accompanied by other ocular defects–eg, congenital cataracts, corneal dystrophy, foveal hypoplasia, and therapeutically refractory glaucoma Prognosis Poor

an·i·rid·i·a

(an'i-rid'ē-ă)
Absence of the iris.
Compare: irideremia

aniridia

Absence of the iris of the eye. This may be CONGENITAL or, more commonly, the result of injury.

aniridia 

Complete, or almost complete, absence of the iris of the eye. It can be acquired, due to trauma, or inherited as an autosomal dominant trait. The patient is photophobic and in congenital cases there is usually amblyopia and sometimes nystagmus. Contact lenses incorporating an artificial iris, or tinted spectacle lenses, help in this condition. See chromosome; irideremia; cosmetic contact lens.

aniridia

congenital complete or partial absence of the iris. Occurs in Jersey calves as an autosomal recessive trait and causes visual impairment, ranging to blindness. May be associated with multiple anomalies such as microphakia and ectopiac lentis.

equine neonatal aniridia
believed to be inherited as an autosomal recessive trait in Belgian horses; sometimes occurs in association with cataracts.
References in periodicals archive ?
lt;<THE North East's first aniridia meeting was held at the weekend to help those with the condition.
Trasplante de membrana amniotica en el tratamiento de la insuficiencia limbal moderada de pacientes con aniridia congenita.
At that stage doctors did not know Marcus had Aniridia like his wife and thought there was little chance of the condition being passed on to any children.
Binocular Coordination Subject Eye Condition Acuity Score(a) 1 Optic atrophy 20/330 0 2 Optic atrophy 20/100 10 3 Macular degeneration 20/120 10 4 Coloboma 20/200 10 5 Optic atrophy 20/35 10 6 Optic atrophy 20/300 0 7 Retinopathy of prematurity 20/300 6 8 Albinism 20/200 0 9 Optic atrophy 20/200 8 10 Rod/cone degeneration 20/80 10 11 Optic nerve hypoplasia 20/250 0 12 Retinitis pigmentosa 20/25 8 13 Marfans syndrome 20/25 10 14 Congenital cataracts 20/50 8 15 Albinism 20/80 9 16 Aniridia 20/300 10 17 Retinopathy of prematurity 20/100 0 18 Albinism 20/120 6 19 Retinitis pigmentosa 20/120 8 20 Congenital nystagmus 20/100 8 21 Hypoplasia 20/200 0 22 Congenital esotropia 20/35 4
1994]: 'Homology of the Eyless Gene of Drosophila to the Small Eye Gene in Mice and Aniridia in Humans', Science, 265, pp.
Homology of the eyeless gene in Drosophila to the small eye gene in mice and aniridia in humans.
Some of the Diseases Mapped by Restriction Fragment Length Polymorphisms (RFLPs) Acoustic neuroma, bilateral Alport syndrome(*1) Amyotrophic lateral sclerosis Aniridia Ataxia telangectasia Charcot-Marie-Tooth disease Craniosyntosis Cystic fibrosis(*1) Duchenne muscular dystrophy(*1) Familial polyposis coli(*1) Fragile X(*1) Friedreich ataxia Hemochromatosis Huntington's disease Kallmann syndrome(*1) Long QT syndrome Multiple endocrine neoplasia, types I and II Myotonic dystrophy Nail-patella syndrome Neurofibromatosis(*1) Polycystic kidney disease Retinoblastoma(*1) Retinitis pigmentosa(*1) von Hippel-Lindau syndrome(*1) Wilms' tumor(*1) Wilson's disease Wiskott-Aldrich syndrome (*1) Indicates diseases in which the gene has been isolated.
1,2,3) It may occur in isolation or in association with conditions such as albinism, aniridia, retinopathy of prematurity, achromatopsia, microphthalmus, myopia, and incontinentia pigmenti.
DISCUSSION: Anterior segment dysgenesis is a group of rare autosomal dominant condition including posterior embryotoxon, Axenfeld-Rieger syndrome, Peter's anomaly and aniridia.
Congenital aniridia is a rare condition (incidence between 1:64000 and 1: 100000) that typically affects both eyes and is associated with PAX6 gene mutations.