angiotensin receptor


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angiotensin receptor

cell-surface G-protein-coupled receptors that mediate the effects of angiotensin II. Two types are recognized: AT1 and AT2. The former mediates the powerful vascular smooth-muscle contraction responsible for the hypertensive response produced by angiotensin II; the latter modulates renin biosynthesis and angiotensin II formation.
References in periodicals archive ?
If you were prescribed an angiotensin-converting enzyme inhibitor, angiotensin receptor blocker, beta-blocker or diuretic, your doctor may have explained that the drug needs to be titrated.
"Certain heart medications like angiotensin receptor blockers [ARBs], angiotensin-converting enzyme [ACE] inhibitors, beta blockers, calcium channel blockers and diuretics, which deplete the body of sodium, can exaggerate the body's response to heat and cause you to feel ill in extreme heat," said Harrington, a cardiologist who heads the Department of Medicine at Stanford University in California.
They analysed the use of angiotensin converting enzyme inhibitor drugs (ACEIs) compared with another group of blood pressure drugs called angiotensin receptor blockers (ARBs).
The study, led by Professor Laurent Azoulay at McGill University in Canada, found that angiotensin converting enzyme inhibitor drugs (ACEIs) to lower blood pressure are associated with an increased risk of lung cancer compared with the use of another group of blood pressure drugs called angiotensin receptor blockers (ARBs).
In December 2017, Carmel Biosciences received FDA approval for PREXXARTAN, the first and only approved oral liquid dosage form of the angiotensin receptor blocker valsartan in the United States.
Conducted by Novartis (VTXL:NOVN), the trial compared the effectiveness of an angiotensin receptor neprilysin inhibitor (ARN), Entresto (sacubitril/valsartan), in comparison to standard treatment with an angiotensin-converting-enzyme (ACE) inhibitor in patients with heart failure and an ejection fraction of 35% or less (the proportion of blood the heart is capable of pumping out of the left ventricle).
Quan, "Fetopathy associated with exposure to angiotensin converting enzyme inhibitors and angiotensin receptor antagonists," Early Human Development, vol.
The review included medications from the five main classes of antihypertensives, including angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, beta-blockers, calcium channel blockers and thiazides.
Additionally, in several animal models of cancer, both angiotensin-converting enzyme (ACE) inhibitors and[ AT.sub.1] angiotensin receptor subtype blockers (ARBs) inhibit tumor growth [7].
Life Extension has recommended a class of drugs called angiotensin receptor II blockers for antihypertensive management over the past several years given the typically good tolerability and efficacy of this drug class.
These include decreased blood volume; chronic kidney insufficiency; congestive heart failure; and taking other medications such as diuretics, blood pressure medicines called angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs), and nonsteroidal anti-inflammatory drugs (NSAIDs).
Many drugs have been tried to reduce progression of diabetic nephropathy and hypertension, but Angiotensin receptor blockers (ARBs) have shown best result.

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