angiotensin I


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Related to angiotensin I: angiotensin II

an·gi·o·ten·sin I

(an'jē-ō-ten'sin),
A decapeptide of slightly variable sequence, depending on the animal source, formed from the tetradecapeptide angiotensinogen by the removal of four amino acid residues, a reaction catalyzed by renin; a peptidase cleaves off a dipeptide (histidylleucine) to yield angiotensin II, the physiologically active form.

angiotensin I

An N-terminal decapeptide produced when renin acts on angiotensinogen. Angiotensin I is the precursor of angiotensin II but itself has no known physiologic role.

angiotensin I

An N-terminal decapeptide produced when renin acts on angiotensinogen; A-I is the precursor of angiotensin II, but itself has no known physiologic role. See Angiotensinogen.

angiotensin I

is converted to angiotensin II by the action of renal renin, causing generalized vasoconstriction and increased blood pressure
References in periodicals archive ?
These drugs prevent that final step in which angiotensin I is converted to active angiotensin II.
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ACE is an enzyme that converts one of the body's chemical messengers, angiotensin I, into angiotensin II.
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In vitro renin inhibition to prevent generation of angiotensins during determination of angiotensin I and II.
Measurement of immunoreactive angiotensin-(I-7) heptapeptide in human blood
Renin is an enzyme that catalyzes the formation of the hormone angiotensin I, which is transformed by the angiotensin converting enzyme (ACE) to angiotensin II, which acts on specific receptors to increase blood pressure and modulate long term processes such as arteriosclerosis and remodeling of heart and kidney.
Merck & Co., Inc. and Actelion Form Renin Inhibitor Alliance
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