angiotensin I


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Related to angiotensin I: angiotensin II

an·gi·o·ten·sin I

(an'jē-ō-ten'sin),
A decapeptide of slightly variable sequence, depending on the animal source, formed from the tetradecapeptide angiotensinogen by the removal of four amino acid residues, a reaction catalyzed by renin; a peptidase cleaves off a dipeptide (histidylleucine) to yield angiotensin II, the physiologically active form.

angiotensin I

An N-terminal decapeptide produced when renin acts on angiotensinogen. Angiotensin I is the precursor of angiotensin II but itself has no known physiologic role.

angiotensin I

An N-terminal decapeptide produced when renin acts on angiotensinogen; A-I is the precursor of angiotensin II, but itself has no known physiologic role. See Angiotensinogen.
References in periodicals archive ?
Harbeson et al., "Angiotensin i is largely converted to angiotensin (1-7) and angiotensin (2-10) by isolated rat glomeruli," Hypertension, vol.
Diabetic nephropathy induced by increased Ace gene dosage is associated with high renal levels of angiotensin (1-7) and bradykinin
(68) Renin snips off a small portion of the angiotensinogen molecule, producing a short amino acid chain called angiotensin I. (5) Another enzyme, angiotensin-converting enzyme (ACE), then makes one final snip to produce the active peptide hormone angiotensin II.
These drugs prevent that final step in which angiotensin I is converted to active angiotensin II.
Natural ways to thwart a stealth killer
Angiotensin I produced Endogenous after an incubation of angiotensin I 1 h at 37 [degrees] C Sample 1 Mean (SD), [micro]/L/h 0.69 (0.14) 0.06 (0.05) CV, % 20.1 84.2 Sample 2 Mean (SD), [micro]/L/h 0.88 (0.12) 0.14 (0.03) CV, % 14.1 22.3 PRA result Sample 1 Mean (SD), [micro]/L/h 0.63 (0.15) CV, % 23.7 Sample 2 Mean (SD), [micro]/L/h 0.73 (0.10) CV, % 13.5
Analytical variation in plasma renin activity: implications for the screening of primary aldosteronism
The angiotensin I converting enzyme (ACE-EC 3.4.15.1) is a widespread zinc-metallopeptidase that converts angiotensin I (AI) to the vasoconstrictor octapeptide angiotensin II (AII).
Inhibition of angiotensin-converting enzyme by quercetin alters the vascular response to bradykinin and angiotensin I. Pharmacol 65, 182-186.
ACE activity during the hypotension produced by standardized aqueous extract of Cecropia glaziovii Sneth: a comparative study to captopril effects in rats
"The present data suggest that angiotensin I receptor blockade improves glucose metabolism at the cellular level, beyond what can be expected by the vasodilatation and blood pressure reduction alone," said Dr.
ARB increases insulin sensitivity in hypertensives
In vitro renin inhibition to prevent generation of angiotensins during determination of angiotensin I and II.
Measurement of immunoreactive angiotensin-(I-7) heptapeptide in human blood
* elucidation of the amino acid composition and sequence of hypertension II and its biochemical relationship to angiotensin I;
Leonard Skeggs to receive Ullman Award
Angiotensin is a hormone that, when converted to angiotensin II, causes your blood vessels to contrict.
Study: angiotensin II may help patients with low blood pressure: Cleveland Clinic researchers found that the compound may treat patients whose arteries open wide, causing a dangerous drop in blood pressure
The findings are "consistent with the concept that angiotensin is involved in contributing to the progression of heart failure and by blocking angiotensin with valsartan, we slowed progression," said Dr.
Diovan. (New & Approved)
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